Cutaneous Morbidity Among Inflammatory Bowel Disease Patients: A Cohort Study

Journal of Crohn's & Colitis
Júlia VideF Magro

Abstract

Patients with inflammatory bowel diseases are prone to cutaneous manifestations. The aim of this study was to investigate their prevalence, type and association to demographic and clinical factors. This was a cross-sectional study. Information relative to patients of a central Portuguese hospital with a definitive diagnosis of an inflammatory bowel disease, who were prospectively recruited, was collected. The final cohort included 342 patients, 62% of whom had Crohn's disease and 38% had ulcerative colitis. Cutaneous extraintestinal manifestations were present in 44.4% of all patients; this prevalence was lower [14.9%] when excluding cutaneous manifestations secondary to nutrition deficiency or drugs. These skin lesions were classified as granulomatous [0.3%], reactive [4.4%], immunologically associated [10.5%] and secondary to nutritional deficiencies [6.4%] or to bowel-related therapy [29.5%]. Excluding those secondary to nutrition or drugs, cutaneous manifestations were significantly associated with females (odds ratio [OR] 3.210 [1.625-6.340], p = 0.001) and younger patients (OR 0.954 [0.924-0.985], p = 0.004). Additionally, their occurrence was related to patients up to 16 years (OR 13.875 [1.332-144.484], p = 0.028) among...Continue Reading

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Citations

Jan 12, 2020·Digestive Diseases and Sciences·Vanessa StatesSusan Galandiuk
Oct 1, 2021·Inflammatory Bowel Diseases·Elena FradkovPeter D R Higgins
Jan 21, 2021·European Journal of Gastroenterology & Hepatology·Dimitra KoumakiIoannis E Koutroubakis

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