Cutaneous polyarteritis nodosa presented with digital gangrene: a case report.

Journal of Korean Medical Science
Seung Won ChoiJae Hoo Park

Abstract

Cutaneous polyarteritis nodosa (CPAN) is an uncommon form of vasculitis involving small and medium sized arteries of unknown etiology. The disease can be differentiated from polyarteritis nodosa by its limitation to the skin and lack of progression to visceral involvement. The characteristic manifestations are subcutaneous nodule, livedo reticularis, and ulceration, mostly localized on the lower extremity. Arthralgia, myalgia, peripheral neuropathy, and constitutional symptoms such as fever and malaise may also be present. We describe a 34-yr-old woman presented with severe ischemic change of the fingertip and subcutaneous nodules without systemic manifestations as an unusual initial manifestation of CPAN. Therapy with corticosteroid and alprostadil induce a moderate improvement of skin lesions. However, necrosis of the finger got worse and the finger was amputated.

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Oct 18, 2013·International Journal of Rheumatic Diseases·Pooja DhaonVini Tandon
Nov 7, 2012·Indian Dermatology Online Journal·Praveen Kumar A SubbannaRathinam P Swaminathan
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Jul 2, 2021·Current Rheumatology Reports·Joana Martins-MartinhoCristina Ponte

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