Cutaneous sarcoidosis clinically mimicking necrobiosis lipoidica in a patient with systemic sarcoidosis.

Annals of Dermatology
Takahito ChibaMasutaka Furue

Abstract

A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granulomas in the dermis. The histological diagnosis was cutaneous sarcoidosis. Systemic sarcoidosis presenting with NL has rarely been reported. The histological features of cutaneous sarcoidosis sometimes mimic those of other granulomatous diseases, including NL and granuloma annulare, which are difficult to distinguish. We discuss the novel association between sarcoidosis and other granulomatous diseases.

References

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Aug 3, 2005·American Journal of Clinical Dermatology·Binh T NgoMarc S Rendell

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Citations

Sep 17, 2014·The British Journal of Dermatology·W FancherA Krunic
May 2, 2018·JAMA Dermatology·Rajsmita BhattacharjeeDipankar De
Sep 15, 2018·Journal of Cutaneous Pathology·Jack LeeMary-Margaret B Noland
Jul 18, 2019·The American Journal of Dermatopathology·Neha ChandanMarylee Braniecki
Oct 31, 2014·The American Journal of Dermatopathology·Joshua M Schulman, Philip E LeBoit
Dec 29, 2020·Health Science Reports·Ingrid CamposGilles Landman
May 8, 2021·International Journal of Dermatology·Galal El EnanyMona R E Abdel-Halim

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Methods Mentioned

BETA
X-ray
bronchoalveolar lavage
biopsies

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