PMID: 6976925Jan 1, 1982Paper

Cutaneous T-cell lymphoma, multilobated type

Histopathology
S C van der PutteJ A van Unnik

Abstract

Three cases of a new type of lymphoma of the skin are described. Clinical manifestations were the development of papules, nodules and tumours which slowly progressed in size and extent in one region of the skin of elderly men. Dissemination to a regional lymph node occurred in only one. Histopathologically the lesions demonstrated a variably perivascular or diffuse dermal infiltrate often with a nodular configuration and sparing the epidermis and a clear subepidermal zone. The infiltrates were dominated by abnormal lymphoid cells with irregular nuclei and blast cells exhibiting a characteristic combination of multilobated nuclei with marginal nucleoli. By immunological and enzyme cytochemical methods the cells were identified as T lymphocytes. It is suggested that the cases described represent different parts of spectrum running from lymphocytoma cutis-like conditions to disseminated malignant lymphoma.

References

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Citations

Oct 1, 1993·International Journal of Dermatology·T NagataniA Sugiyama
Jan 1, 1984·Archives of Dermatological Research·S C van der PutteJ A van Unnik
Jan 1, 1984·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·S C van der PutteJ A van Unnik
Aug 1, 1993·Journal of the American Academy of Dermatology·C de la TorreM T Yebra
Oct 1, 1985·Journal of the American Academy of Dermatology·J M WolffE Abell
Aug 1, 1991·Journal of the American Academy of Dermatology·B D GoldmanE C Vonderheid
Mar 1, 1984·European Journal of Cancer & Clinical Oncology·H P Honegger, F Cavalli
Jan 1, 1987·Arthritis and Rheumatism·D A IsenbergR L Souhami
Nov 1, 1983·The Journal of Pathology·E L Jones
Aug 15, 1984·Cancer·S H SwerdlowA G Stansfeld
Apr 1, 1988·Cancer·J van BaarlenJ A van Unnik
Jan 1, 1986·Ultrastructural Pathology·N Pinel-BriquelP Stoebner

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