Cyanide, haematology and histopathology profiles of albino rats fed with 'Fufu'-based diets produced from mixed starter cultures

Heliyon
C Y BabatuyiV N Enujiugha

Abstract

The cyanide, haematology and histopathology profiles of white albino rats fed with 'fufu'-based diets were monitored. The cassava tubers were subjected into different processing operations: spontaneous-soaked traditional method (SWI), grated before spontaneously-fermented without starter culture (CWI) and those grated, blanched at 65 °C for 15 min before fermented with microorganisms isolated, purified and identified from spontaneously fermented 'fufu' categorized into Bacteria only (BAP), Bacteria and Yeast (BYP), Yeast only (YAP), Bacteria and Mould (BMP), Mould and Yeast (MYP) and Mould only (MAP) and were oven dried and milled. The commercial ready-to-eat 'Fufu' (CWF) was served as control for laboratory processed samples. Albino rats of the wister strain with four (4) rats per group were fed with 50 % of Commercial vital feed (CVF) and 50% each of the remaining nine (9) "Fufu" samples in ratio 1:1 before haematology and histopathology profile of the animals were investigated. It was found out that Samples BMP and MAP had abnormal high Neutrophil (58-60; 41-42 %) lower Lymphocyte (40-43; 58-61 %), lower Packed cell volume (46-48; 45-47 %) and higher cyanide in the blood (0.004-0.006 mg/L) with sample BMP highest white blood...Continue Reading

References

Jul 27, 1999·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·L CarlssonH Rosling
Mar 4, 2010·Annals of Tropical Paediatrics·B N AkyildizA Tunç
May 21, 2016·Frontiers in Microbiology·Jyoti P TamangSoo-Wan Chae

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