Cyanolide A, a glycosidic macrolide with potent Molluscicidal activity from the Papua New Guinea cyanobacterium Lyngbya bouillonii.

Journal of Natural Products
Alban R PereiraW H Gerwick

Abstract

Over the last 50 years, molluscicides have played a critical role in the control of schistosomiasis transmission. Cyanolide A (2), isolated from extracts of a Papua New Guinea collection of Lyngbya bouillonii, is a new and highly potent molluscicidal agent against the snail vector Biomphalaria glabrata (LC(50) = 1.2 microM). The structure of cyanolide A (2) was elucidated through extensive NMR spectroscopic analyses, yielding a symmetrical dimer that represents the newest addition to the family of glycosidic macrolides from cyanobacteria.

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Citations

Jun 7, 2011·Journal of the American Chemical Society·Michael R Gesinski, Scott D Rychnovsky
Apr 9, 2011·Journal of Natural Products·Alban R PereiraWilliam H Gerwick
Apr 12, 2013·Biofouling·Sergey DobretsovMax Teplitski
Jan 15, 2013·Applied and Environmental Microbiology·Niclas EngeneValerie J Paul
Oct 20, 2010·Current Opinion in Biotechnology·Katharine R WattsPhillip Crews
Sep 10, 2014·The Journal of Organic Chemistry·Gidget C TayScott D Rychnovsky
Oct 8, 2016·Natural Product Reports·Kiyoun LeeJiyong Hong
Sep 13, 2011·Journal of Applied Toxicology : JAT·M NagarajanM Sundararaman
Dec 24, 2011·Natural Product Reports·John W BluntMichèle R Prinsep
Apr 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lena KellerWilliam H Gerwick
Dec 15, 2010·Organic & Biomolecular Chemistry·Zhen YangXuegong She
Apr 27, 2017·Marine Drugs·Mengchuan WangXiaojun Yan
Nov 17, 2019·Journal of Photochemistry and Photobiology. B, Biology·Susana Fuentes-TristanDanay Carrillo-Nieves
Jan 23, 2021·RSC Medicinal Chemistry·Godwin Akpeko DziwornuKelly Chibale
Jul 12, 2020·European Journal of Medicinal Chemistry·Jianzhou XuLijian Ding
May 25, 2010·Organic Letters·Hyoungsu Kim, Jiyong Hong
Aug 26, 2011·The Journal of Organic Chemistry·Robert J Sharpe, Michael P Jennings
Feb 2, 2011·The Journal of Organic Chemistry·Srihari PabbarajaJ S Yadav
Jan 5, 2011·The Journal of Organic Chemistry·Atul K HajareD Srinivasa Reddy
Nov 11, 2017·The Journal of Organic Chemistry·Kotaro IwasakiMakoto Sasaki

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