Cycasin: detection of associated mutagenic activity in vivo

Science
M G GabridgeM S Legator

Abstract

Cycasin and its lagycone, methylazoxymethanol, increase the mutant frequency of Salmonella typhimurium histidine auxotrophs when tested in the hostmediated assay. As expected, the degree of cycasin-related mutagenic activity depends on the facility with which the compound can be enzymatically deglucosylated by the normal intestinal flora.

References

Mar 1, 1969·Proceedings of the Society for Experimental Biology and Medicine·M G Gabridge, M S Legator
Mar 1, 1967·Proceedings of the Society for Experimental Biology and Medicine·M SpatzG L Laqueur
Feb 1, 1966·Proceedings of the Society for Experimental Biology and Medicine·M SpatzG L Laqueur

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Citations

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Jan 1, 1976·Chemico-biological Interactions·K Shinohara, H Matsudaira
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Dec 1, 1971·Langenbecks Archiv für Chirurgie·R Preussmann
Feb 1, 1983·Applied and Environmental Microbiology·V W Mayer, C J Goin
Jun 4, 1971·Science·P E HartmanH Berger

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