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Cyclic AMP and cyclic GMP concentrations in serum- and density-restricted fibroblast cultures

Proceedings of the National Academy of Sciences of the United States of America

Mar 1, 1975

W MoensR Kram

PMID: 165482

Abstract

Mouse fibroblasts transformed by simian virus 40 (SV3T3 cells) are characterized by cyclic AMP and cyclic GMP levels, respectively, about half and twice those found in growing untransformed 3T3 cells. Density-dependent inhibition of growth is correlated with reduced cyclic GMP concentra...read more

Mentioned in this Paper

Simian virus 40
Cell Division Phases
Blood
Contact Inhibition
Cyclic AMP, (R)-Isomer
Fibroblasts
Cyclic GMP
Neoplastic Cell Transformation
6
Paper Details
References
  • References28
  • Citations44
123
  • References28
  • Citations44
12345

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Intracellular cyclic AMP concentration responds specifically to growth regulation by serum

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Cyclic AMP and cyclic GMP concentrations in serum- and density-restricted fibroblast cultures

Proceedings of the National Academy of Sciences of the United States of America

Mar 1, 1975

W MoensR Kram

PMID: 165482

DOI:

Abstract

Mouse fibroblasts transformed by simian virus 40 (SV3T3 cells) are characterized by cyclic AMP and cyclic GMP levels, respectively, about half and twice those found in growing untransformed 3T3 cells. Density-dependent inhibition of growth is correlated with reduced cyclic GMP concentra...read more

Mentioned in this Paper

Simian virus 40
Cell Division Phases
Blood
Contact Inhibition
Cyclic AMP, (R)-Isomer
Fibroblasts
Cyclic GMP
Neoplastic Cell Transformation
6

Similar Papers Found In These Feeds

sGC Modulators

Soluble guanylate cyclase (sGC) stimulators and activators have been developed to treat patients with pulmonary hypertension and heart failure, respectively. Recently these sGC modulators have been explored for the treatment of fibrosis. Discover the latest research on sGC modulators here.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Intracellular cyclic AMP concentration responds specifically to growth regulation by serum

Proceedings of the National Academy of Sciences of the United States of AmericaMarch 1, 1974
J OeyR Pollack
Paper Details
References
  • References28
  • Citations44
123
  • References28
  • Citations44
12345
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