Cyclic contrast-enhanced harmonic voiding urosonography for the evaluation of reflux. Can we keep the cost of the examination low?

European Radiology
Frederica PapadopoulouStavros C Efremidis

Abstract

The purpose of this study was to evaluate whether a second cycle of contrast-enhanced voiding urosonography (VUS) with no added contrast medium (CM) can increase the detection rate of vesicoureteral reflux (VUR). One hundred twelve consecutive children with a mean age of 2.9 years with 224 kidney-ureter units (KUU) underwent two cycles of contrast-enhanced harmonic VUS. The first cycle of VUS was performed with 3.5-12.5 ml of suspension 300 mg/ml SH U 508 A and was followed immediately by a second cycle with only saline without adding CM. VUR was detected in 57 KUU from 44 children (39%) at the first cycle of VUS. Eight of the remaining 68 non-refluxing children (12%) demonstrated VUR at the second cycle (P=0.045). Most cases of missed reflux at the first cycle were grade II (75%). However, in two KUU from two children missed reflux was grade III. In one child reflux (grade II) was missed on the second cycle. Comparing the second cycle of VUS with the first cycle, concordant findings regarding the presence or absence as well as the grade of reflux were found in 94% of KUU. A second cycle of contrast-enhanced harmonic VUS with no added CM discloses significantly more cases of VUR at no additional cost for the examination.

References

Nov 1, 1992·The Journal of Urology·R L Lebowitz
Nov 1, 1992·The Journal of Urology·H N Noe
Dec 11, 1992·The Journal of Urology·H N NoeM L Rivas
Mar 1, 1990·British Journal of Urology·D C HanburyT Sherwood
Oct 1, 1989·AJR. American Journal of Roentgenology·S Jequier, J C Jequier
Jan 1, 1983·Urologic Radiology·U Willi, S Treves
Feb 1, 1983·AJR. American Journal of Roentgenology·R L Lebowitz, J G Blickman
Apr 1, 1995·The Journal of Urology·J T SongD A Bloom
Aug 1, 1996·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·D SiamplisI Fezoulidis
Sep 2, 1999·AJR. American Journal of Roentgenology·H J MentzelW A Kaiser
Apr 25, 2000·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·R B KendaJ J Fettich
Aug 10, 2000·European Journal of Radiology·R FarinaA Di Benedetto
Feb 24, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·A KmetecJ Buturovic-Ponikvar
Feb 24, 2001·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·I EscapeP Sala
Oct 30, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·R B KendaJ B Ponikvar
Nov 22, 2001·AJR. American Journal of Roentgenology·K DargeJ Troeger
Jan 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kassa Darge
Feb 8, 2002·The Journal of Urology·Christian RadmayrFerdinand Frauscher
Mar 1, 2002·European Radiology·Frederica PapadopoulouAnastasia Economou
Jul 20, 2002·European Journal of Radiology·Kassa Darge, Jochen Troeger
Aug 5, 2003·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Gregor NovljanRajko B Kenda
Nov 14, 1964·British Medical Journal·J M SMELLIEI C NORMAND
Feb 1, 1965·The Journal of Urology·E A TANAGHOO N RAMBO
Nov 1, 1961·The Journal of Urology·J A HUTCH
Jul 3, 2004·European Radiology·Andrea KopitzkoThomas Albrecht
Sep 28, 2004·Pediatric Radiology·Kassa DargeHubertus Riedmiller

❮ Previous
Next ❯

Citations

Jan 12, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Constantinos J Stefanidis, Ekaterini Siomou
May 22, 2010·The Journal of Urology·Gregor NovljanRajko B Kenda
Oct 6, 2017·Abdominal Radiology·Aikaterini NtouliaSusan J Back
Feb 27, 2021·Journal of Ultrasound·Andrea Cvitkovic-RoicGoran Roic

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.