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Cyclic nucleotides and growth control in cultured mouse cells: correlation of changes in intracellular 3':5' cGMP concentration with a specific phase of the cell cycle

Proceedings of the National Academy of Sciences of the United States of America

Dec 1, 1974

Wilfried Seifert, Philip Spencer Rudland

PMID: 4373735

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Abstract

The commencement of cell growth following serum addition to quiescent cultures of mouse fibroblasts is preceded by transient changes in intracellular concentrations of cAMP and cGMP. By artificial depletion of the culture medium for different nutrients, cell growth can be reversibly arr...read more

Mentioned in this Paper

Cyclic GMP
Orthophosphate
D-Glutamine
Nucleotides, Cyclic
Tritium
Specimen Type - Fibroblasts
Fibroblasts
Pedameth
Thymidine
Cyclic AMP, (R)-Isomer
Paper Details
References
    • References22
    • Citations44
    • References22
    • Citations44
  • Cyclic nucleotides and growth control in cultured mouse cells: correlation of changes in intracellular 3':5' cGMP concentration with a specific phase of the cell cycle

    Proceedings of the National Academy of Sciences of the United States of America

    Dec 1, 1974

    Wilfried Seifert, Philip Spencer Rudland

    PMID: 4373735

    DOI:

    Abstract

    The commencement of cell growth following serum addition to quiescent cultures of mouse fibroblasts is preceded by transient changes in intracellular concentrations of cAMP and cGMP. By artificial depletion of the culture medium for different nutrients, cell growth can be reversibly arr...read more

    Mentioned in this Paper

    Cyclic GMP
    Orthophosphate
    D-Glutamine
    Nucleotides, Cyclic
    Tritium

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    Paper Details
    References
    • References22
    • Citations44
    • References22
    • Citations44
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