Cyclic ruthenium-alkylidene catalysts for ring-expansion metathesis polymerization.

Journal of the American Chemical Society
Andrew J BoydstonRobert H Grubbs

Abstract

A series of cyclic Ru-alkylidene catalysts have been prepared and evaluated for their efficiency in ring-expansion metathesis polymerization (REMP). The catalyst structures feature chelating tethers extending from one N-atom of an N-heterocyclic carbene (NHC) ligand to the Ru metal center. The catalyst design is modular in nature, which provided access to Ru complexes having varying tether lengths, as well as electronically different NHC ligands. Structural impacts of the tether length were unveiled through (1)H NMR spectroscopy as well as single-crystal X-ray analyses. Catalyst activities were evaluated via polymerization of cyclooctene, and key data are provided regarding propagation rates, intramolecular chain transfer, and catalyst stabilities, three areas necessary for the efficient synthesis of cyclic poly(olefin)s via REMP. From these studies, it was determined that while increasing the tether length of the catalyst leads to enhanced rates of polymerization, shorter tethers were found to facilitate intramolecular chain transfer and release of catalyst from the polymer. Electronic modification of the NHC via backbone saturation was found to enhance polymerization rates to a greater extent than did homologation of the teth...Continue Reading

References

Feb 15, 2001·Accounts of Chemical Research·T M Trnka, R H Grubbs
Jul 6, 2001·Journal of the American Chemical Society·M S SanfordR H Grubbs
Oct 24, 2001·The Journal of Organic Chemistry·K. J. SheaB. B. Busch
Jul 6, 2002·Organic Letters·Robert M OwenLaura L Kiessling
Sep 21, 2002·Science·Christopher W BielawskiRobert H Grubbs
Feb 27, 2003·Journal of the American Chemical Society·Tina M TrnkaRobert H Grubbs
Jul 10, 2003·Journal of the American Chemical Society·Christopher W BielawskiRobert H Grubbs
Jun 5, 2004·Organic Letters·Eric C Hansen, Daesung Lee
Oct 14, 2005·Journal of the American Chemical Society·Arnab K ChatterjeeRobert H Grubbs
Feb 9, 2006·Journal of the American Chemical Society·Timothy W FunkRobert H Grubbs
Mar 30, 2006·Journal of the American Chemical Society·Boyd A Laurent, Scott M Grayson
Nov 1, 2006·Angewandte Chemie·Stefan HilfAndreas F M Kilbinger
Oct 2, 2007·Journal of the American Chemical Society·Irina A GorodetskayaRobert H Grubbs
Jan 17, 2008·Journal of the American Chemical Society·Yan XiaJulia A Kornfield
Jan 29, 2008·Journal of the American Chemical Society·Georgios C Vougioukalakis, Robert H Grubbs

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Citations

Apr 22, 2011·Journal of the American Chemical Society·Ke ZhangGregory N Tew
Jan 14, 2012·Journal of the American Chemical Society·Benjamin K KeitzRobert H Grubbs
Aug 9, 2013·Journal of the American Chemical Society·Joshua A KaitzJeffrey S Moore
Aug 13, 2013·Journal of the American Chemical Society·Ke ZhangGregory N Tew
Feb 10, 2009·Journal of the American Chemical Society·Yan XiaRobert H Grubbs
Apr 2, 2009·Journal of the American Chemical Society·Wonhee JeongRobert M Waymouth
Apr 2, 2009·Journal of the American Chemical Society·Andrew J BoydstonRobert H Grubbs
Nov 19, 2009·Journal of the American Chemical Society·William D Jones
Feb 18, 2010·Journal of the American Chemical Society·Paul G ClarkRobert H Grubbs
Jun 1, 2009·Nature Chemistry·Scott M Grayson
Jul 23, 2009·Chemical Society Reviews·Boyd A Laurent, Scott M Grayson
Jul 5, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Jian-Yi Chen, Ming-Der Su
May 26, 2009·Journal of Controlled Release : Official Journal of the Controlled Release Society·Bo ChenFrancis C Szoka
Dec 18, 2013·Journal of Gerontological Social Work·Mariko A FoulkHelen C Kales
Jul 22, 2016·Nature Chemistry·Christopher D RolandAdam S Veige
Mar 15, 2011·Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie·Denise Reid
Dec 13, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Kotohiro Nomura, Xiaohua Hou
Mar 10, 2015·Journal of Holistic Nursing : Official Journal of the American Holistic Nurses' Association·Nasrin Falsafi, Louisa Leopard
May 2, 2018·Chemical Society Reviews·O M OgbaR H Grubbs
May 19, 2011·Angewandte Chemie·Yan XiaRobert H Grubbs
Apr 5, 2011·Journal of Computational Chemistry·Chi-Shiun Wu, Ming-Der Su
Nov 5, 2015·PloS One·Nicholas T Van DamJudson A Brewer
Jan 12, 2019·Chemical Communications : Chem Comm·Veronica CartaMark J MacLachlan
Feb 3, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Chi-Shiun Wu, Ming-Der Su
Oct 28, 2019·Chemical Communications : Chem Comm·Christopher D RolandAdam S Veige
Apr 7, 2020·Nature Chemistry·Farihah M Haque, Scott M Grayson
Oct 30, 2016·Angewandte Chemie·Thomas JosseOlivier Coulembier
Oct 20, 2015·ChemistryOpen·Yinghuai Zhu, Narayan S Hosmane
Apr 15, 2010·Chemistry, an Asian Journal·Zhibin Guan
Feb 1, 2010·Organometallics·Benjamin K Keitz, Robert H Grubbs
Dec 17, 2009·Chemical Reviews·Georgios C Vougioukalakis, Robert H Grubbs
Jun 19, 2009·Chemical Reviews·Cezary SamojłowiczKarol Grela
Jun 23, 2009·Chemical Reviews·Sebastien Monfette, Deryn E Fogg
May 8, 2021·Journal of the American Chemical Society·Teng-Wei WangMatthew R Golder
Mar 1, 2011·Journal of the American Chemical Society·Ke ZhangGregory N Tew
Jul 10, 2019·Journal of the American Chemical Society·Yangju LinStephen L Craig

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