Cyclic sulfoxides-garlicnins K1, K2, and H1-extracted from Allium sativum

Chemical & Pharmaceutical Bulletin
Toshihiro NoharaMotohiro Takeya

Abstract

Newly identified cyclic sulfoxides-garlicnins K1 (1), K2 (2), and H1 (3)-were isolated from the acetone extracts of the bulbs of garlic, Allium sativum. Garlicnin H1 (3) demonstrated potential to suppress tumor cell proliferation by regulating macrophage activation. The structures of garlicnins K1 and K2, 3,4-dimethyl-5-allyl-tetrahydrothiophen-2-one-S-oxides, and the structure of garlicnin H1, 3-carboxy-3-hydroxy-4-methyl-5-allylsulfoxide-tetrahydrothiophen-2-(ethane-1,2-diol)-S-oxide were characterized by spectroscopic analysis.

References

Jul 19, 2001·Journal of the National Cancer Institute·C Theisen
Jan 4, 2003·Nature Reviews. Immunology·Siamon Gordon
Jan 21, 2006·Cancer Research·Claire E Lewis, Jeffrey W Pollard
Feb 18, 2006·The Journal of Nutrition·Harunobu Amagase
Mar 7, 2006·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Yoshihiro KomoharaMotohiro Takeya
Mar 8, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Antonio SicaPaola Allavena
May 10, 2008·Seminars in Cancer Biology·Antonio SicaAlberto Mantovani
Mar 13, 2009·Nature Reviews. Cancer·Johanna A Joyce, Jeffrey W Pollard
Jul 6, 2010·Journal of Natural Products·Mona El-AasrToshihiro Nohara
Nov 2, 2011·Chemical & Pharmaceutical Bulletin·Mona El-AasrToshihiro Nohara
Jun 13, 2012·Chemical & Pharmaceutical Bulletin·Toshihiro NoharaJunei Kinjo
Jul 3, 2013·Chemical & Pharmaceutical Bulletin·Toshihiro NoharaJunei Kinjo
May 3, 2014·Chemical & Pharmaceutical Bulletin·Toshihiro NoharaJunei Kinjo

❮ Previous
Next ❯

Citations

Oct 16, 2015·Journal of the American Chemical Society·Tiezheng JiaPatrick J Walsh
Jan 5, 2017·Chemical & Pharmaceutical Bulletin·Masateru OnoToshihiro Nohara
Mar 3, 2017·Chemical & Pharmaceutical Bulletin·Toshihiro NoharaJunei Kinjo
Jun 21, 2016·Chemical Communications : Chem Comm·Mukund M D Pramanik, Namrata Rastogi
Dec 18, 2015·Journal of Natural Medicines·Toshihiro NoharaJunei Kinjo
May 15, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Igor A SchepetkinMark T Quinn
May 21, 2021·Planta medica·Junchi WangJianyong Si
Jan 30, 2019·Organic Letters·Chen WuPatrick J Walsh
May 26, 2017·Journal of the American Chemical Society·Tiezheng JiaPatrick J Walsh
Nov 20, 2021·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Lu YangQingle Zeng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Chemical & Pharmaceutical Bulletin
Toshihiro NoharaJunei Kinjo
Journal of Natural Products
Mona El-AasrToshihiro Nohara
© 2022 Meta ULC. All rights reserved