Cyclic Vomiting Syndrome in Children and Adults: What Is New in 2018?

Current Gastroenterology Reports
Katja KovacicThangam Venkatesan

Abstract

Cyclic vomiting syndrome (CVS) is a disabling functional gastrointestinal disorder characterized by severe vomiting episodes that alternate with symptom-free periods. The purpose of this review is to summarize current knowledge and highlight most recent data on prevalence, diagnosis, management, and impact of CVS in children and adults. Originally thought to be a pediatric disorder, the past decade has witnessed a considerable increase in CVS diagnosed in adults. Despite improved recognition of CVS, without a delineated pathophysiology and specific biomarker, it remains classified as a functional gastrointestinal disorder. Migraines and CVS share a common pathway based on several studies and response to migraine therapy. Recent work has begun to expand the list of comorbidities and identify plausible mechanisms and new therapeutic avenues. This review seeks to highlight best practices and novel therapies for CVS based on expert consensus and review of available literature.

References

Nov 1, 1995·Journal of Pediatric Gastroenterology and Nutrition·I Abu-Arafeh, G Russell
Jul 1, 1997·Journal of Pediatric Gastroenterology and Nutrition·R GokhaleB S Kirschner
May 6, 1999·The Journal of Pediatrics·B U LiJ R Hayes
Aug 6, 1999·Journal of the American Academy of Child and Adolescent Psychiatry·H GutgesellK A Taubert
Mar 31, 2001·The American Journal of Gastroenterology·C PrakashR E Clouse
Jul 8, 2003·American Journal of Therapeutics·Tariq A KhasawinahJoseph D Tobias
Nov 1, 2006·Pediatric Neurology·Akgün OlmezGüzide Turanli
Nov 15, 2006·The American Journal of Gastroenterology·Adeyemi LawalBenson T Massey
Dec 13, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ray E ClouseChandra Prakash
Feb 28, 2007·Journal of Pediatric Gastroenterology and Nutrition·Thomas C Chelimsky, Gisela G Chelimsky
May 1, 2007·World Journal of Gastroenterology : WJG·Mahmood HaghighatMarzieh Nejabat
Mar 29, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·T L AbellN Vakil
Aug 30, 2008·Journal of Pediatric Gastroenterology and Nutrition·B U K LiUNKNOWN North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition
Aug 30, 2008·Brain & Development·Toshiyuki HikitaYukishige Yanagawa
Feb 26, 2010·BMC Emergency Medicine·Thangam VenkatesanB U K Li
Aug 21, 2010·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·R A HejaziR W McCallum
Nov 9, 2010·Journal of the American Board of Family Medicine : JABFM·Dale A PattersonMark Walsh
Jun 15, 2011·Alimentary Pharmacology & Therapeutics·R A Hejazi, R W McCallum
May 6, 2014·Experimental Brain Research·Thangam VenkatesanMartin Storr
May 28, 2014·Experimental Brain Research·Reza A Hejazi, Richard W McCallum
Jun 6, 2014·Alimentary Pharmacology & Therapeutics·F CristoforiO Borrelli
Apr 24, 2015·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Howard S KimAndrew A Monte
May 5, 2016·Gastroenterology·Jeffrey S HyamsMiranda van Tilburg
Jun 1, 2016·Journal of Neurogastroenterology and Motility·Inderpreet GroverThomas L Abell
Aug 25, 2016·Autonomic Neuroscience : Basic & Clinical·Sally E TarbellJohn E Fortunato
Oct 21, 2016·Current Treatment Options in Gastroenterology·Sanjay Bhandari, Thangam Venkatesan
Dec 3, 2016·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·D-M EllingsenV Napadow
Dec 22, 2016·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Cecilia J SorensenAndrew A Monte
May 10, 2017·Journal of Clinical Pharmacy and Therapeutics·D F Thompson, H S Saluja
Jul 27, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·R C SagarA C Ford
Jan 27, 2018·Journal of Pediatric Gastroenterology and Nutrition·Chantal J Lucia-CasadonteAshish S Chogle
Feb 15, 2018·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Sanjay BhandariThangam Venkatesan

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Citations

Jan 29, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Mohamed Tausif SiddiquiDonald F Kirby
Jul 25, 2019·Current Opinion in Pediatrics·Bradley JersonMiranda A L van Tilburg
Oct 30, 2020·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Mahesh GajendranRichard McCallum
Apr 6, 2021·Journal of Pharmacy Practice·Fiona CheungAlexandra W Tatara
May 28, 2021·Nature Reviews. Neurology·Ishaq Abu-Arafeh, Amy A Gelfand
Jun 12, 2021·Alimentary Pharmacology & Therapeutics·Harrison MooersThangam Venkatesan
Oct 14, 2021·Journal of Neurogastroenterology and Motility·Léa LenglarTLuigi Titomanlio
Nov 5, 2021·Forensic Science, Medicine, and Pathology·Ingo von Both, Brittini Santos

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