Cyclical variation in the incidence of childhood-onset type 1 diabetes during 40 years in Navarra (Spain)

Pediatric Diabetes
Luis ForgaMaría José Goñi

Abstract

To trace the evolution of type 1 diabetes (T1D) in Navarre in children under 15, between 1977 and 2016, and their characteristics at onset regarding age and sex. We performed a descriptive analysis, using prospective-retrospective information. The study included all cases of T1D diagnosed in Navarre in children aged 0 to 14 years old from 1 January 1977 until 31 December 2016. The capture-recapture method was used, retrieving information from three independent sources: the five hospitals in Navarre as a primary source, and the Navarre Association of Diabetics (ANADI) and the primary healthcare system as the secondary source. Estimates and confidence intervals were calculated assuming a subjacent Poisson distribution. Chi square test was used to compare incidence between groups. The analysis of changes in incidence since 1977, adjusted for age group, sex and year of diagnosis, were evaluated with a multivariate Poisson regression model and joinpoint regression. A total of 577 cases were registered resulting in a crude incidence rate of 14.99/100 000 inhabitants-year (95% confidence interval [CI]: 13.79-16.26). From 1977, the incidence has increased in cycles, reaching an incidence rate of 22.98 (95% CI: 18.52-28.21) in 2016. The...Continue Reading

References

Jun 1, 1997·Acta Paediatrica·M ChuecaA Sola
Aug 17, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·UNKNOWN DIAMOND Project Group
Mar 15, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·A-K Imkampe, M C Gulliford
Jun 18, 2011·Diabetes Care·Gisela G DahlquistUNKNOWN Diabetes Incidence in Sweden Study Group
Nov 9, 2011·Pediatric Diabetes·Eva Krisztina GyurusUNKNOWN Hungarian Childhood Diabetes Epidemiology Group
Jan 29, 2014·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·S Conde BarreiroM L Compés Dea
Aug 12, 2014·Gaceta sanitaria·Luis Forga LlenasSara Berrade Zubiri
Apr 8, 2015·BMC Public Health·Paula A Diaz-ValenciaAlain-Jacques Valleron
Nov 4, 2015·Diabetes Research and Clinical Practice·Agostino Di Ciaula
Jan 20, 2016·Pediatric Diabetes·Concepción Fernández-RamosItxaso Rica
Apr 20, 2016·Journal of Diabetes Research·F FortunatoUNKNOWN Apulian Childhood-Onset Diabetes Registry Workgroup
Mar 31, 2017·Nature Reviews. Disease Primers·Anastasia KatsarouÅke Lernmark
Apr 10, 2017·Diabetes Research and Clinical Practice·Carlos Antonio NegratoMarilia Brito Gomes
Apr 14, 2017·The New England Journal of Medicine·Elizabeth J Mayer-DavisUNKNOWN SEARCH for Diabetes in Youth Study
Oct 31, 2017·The Lancet. Diabetes & Endocrinology· The Lancet Diabetes Endocrinology

❮ Previous
Next ❯

Citations

Mar 6, 2021·Endocrinología, Diabetes Y Nutrición·Fernando Gómez-PeraltaUNKNOWN en nombre de la SED y de los investigadores del estudio SED1

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.

Related Papers

Anales del sistema sanitario de Navarra
Luis ForgaMaría Chueca
Endocrinología, Diabetes Y Nutrición
Luis Forgaen representación del Grupo de Estudio de Diabetes tipo 1 de Navarra
Diabetes Research and Clinical Practice
Clara PiffarettiSandrine Fosse-Edorh
© 2022 Meta ULC. All rights reserved