Nov 20, 2013

Cycling Physicochemical Gradients as ‘Evolutionary Drivers’: From Complex Matter to Complex Living States

BioRxiv : the Preprint Server for Biology
Jan Spitzer


Highlights Abstract Within the overlap of physics, chemistry and biology, complex matter becomes ‘more deeply’ understood when high level mathematics converts regularities of experimental data into scientific laws, theories, and models ([Krakauer et al., 2011][1]. The challenges and scope of theoretical biology . J. Theoret. Biol. 276: 269–276). The simplest kinds of complex biological matter are bacterial cells; they appear complex–from a physicochemical standpoint–because they are multicomponent, multiphase, biomacromolecularly crowded, and re-emergent; the property of re-emergence differentiates biological matter from complex chemical and physical matter. Bacterial cells cannot self-reassemble spontaneously from their biomolecules and biomacromolecules (via non-covalent molecular forces) without the action of external ‘drivers’; on Earth, such drivers have been diurnal (cycling) physicochemical gradients, i.e . temperature, water activity, etc. brought about by solar radiation striking the Earth’s rotating surface. About 3.5 billion years ago, these cycling gradients drove complex chemical ‘prebiotic soups’ toward progenotic living states from which extant bacteria evolved ([Spitzer and Poolman, 2009][2]; The role of biom...Continue Reading

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Mentioned in this Paper

Covalent Interaction
CDC7 gene
Complex (molecular entity)
Spatial Distribution
Golgi Reassembly
Tooth Crowding
Visual Perception
Ion Channel
Cell Cycle

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