journal cover

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond-forming enzymes

Nature Chemical Biology

May 12, 2009

Muriel GondryJean-Luc Pernodet

Abstract

Cyclodipeptides and their derivatives belong to the diketopiperazine (DKP) family, which is comprised of a broad array of natural products that exhibit useful biological properties. In the few known DKP biosynthetic pathways, nonribosomal peptide synthetases (NRPSs) are involved in the ...read more

Mentioned in this Paper

Biochemical Pathway
Bacterial Proteins
Derivatives
Enzymes, antithrombotic
Natural Products
Albonoursin
MT-TA gene
Triplet Codon-amino Acid Adaptor Activity
Transfer RNA
Substrate Specificity
2
1
131
Paper Details
References
  • References30
  • Citations76
123
  • References30
  • Citations76
12345...

Similar Papers Found In These Feeds

Molecular Bacteriology

Molecular bacteriology involves fundamental, translational and application-oriented research on the very diverse roles of bacteria in human health and disease. Discover the latest on molecular bacteriology here.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog

Proceedings of the National Academy of Sciences of the United States of AmericaFebruary 18, 2011
Luc BonnefondOsamu Nureki
Nature Chemical Biology

The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase

Nature Chemical BiologySeptember 21, 2010
Matthew W VettingJohn S Blanchard
© 2020 Meta ULC. All rights reserved

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond-forming enzymes

Nature Chemical Biology

May 12, 2009

Muriel GondryJean-Luc Pernodet

PMID: 19430487

DOI: 10.1038/nchembio.175

Abstract

Cyclodipeptides and their derivatives belong to the diketopiperazine (DKP) family, which is comprised of a broad array of natural products that exhibit useful biological properties. In the few known DKP biosynthetic pathways, nonribosomal peptide synthetases (NRPSs) are involved in the ...read more

Mentioned in this Paper

Biochemical Pathway
Bacterial Proteins
Derivatives
Enzymes, antithrombotic
Natural Products
Albonoursin
MT-TA gene
Triplet Codon-amino Acid Adaptor Activity
Transfer RNA
Substrate Specificity
2
1
131

Similar Papers Found In These Feeds

Molecular Bacteriology

Molecular bacteriology involves fundamental, translational and application-oriented research on the very diverse roles of bacteria in human health and disease. Discover the latest on molecular bacteriology here.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog

Proceedings of the National Academy of Sciences of the United States of AmericaFebruary 18, 2011
Luc BonnefondOsamu Nureki
Nature Chemical Biology

The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase

Nature Chemical BiologySeptember 21, 2010
Matthew W VettingJohn S Blanchard
Paper Details
References
  • References30
  • Citations76
123
  • References30
  • Citations76
12345...
/papers/cyclodipeptide-synthases-are-a-family-of-trna-depe/19430487