Jan 1, 2009

Cynaratriol, a sesquiterpene lactone from Centaurea musimomum

Acta Crystallographica. Section E, Structure Reports Online
Matías López-RodríguezFadila Benayache


THE TITLE COMPOUND [SYSTEMATIC NAME: 3,8-dihydr-oxy-3-(hydroxy-meth-yl)-9-methyl-6-methyl-enedeca-hydro-azuleno[4,5-b]furan-2(3H)-one], C(15)H(22)O(5), is a sesquiterpene lactone showing the typical tricyclic guaianolide skeleton which has been isolated, together with other related metabolites, from the plant Centaurea musimomum. The present study confirms the mol-ecular structure, assigned by (1)H NMR and MS spectroscopy, as well as the the 11β-hydroxy-methyl, 3β-hydr-oxy and 4α-methyl stereochemistry. The crystal structure is built through a network of O-H⋯O hydrogen bonds involving the three hydroxyl groups that are present in the mol-ecular skeleton.

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Mentioned in this Paper

Skeletal System
5-methyltetrahydrofolate-homocysteine S-methyltransferase Activity
Crystal Structure
Stereochemistry (Molecular Function)
Spectrum Analysis

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