Cyr61 is a potential prognostic marker for prostate cancer.

Asian Journal of Andrology
Naoki TeradaRobert H Getzenberg

Abstract

Cysteine-rich angiogenic inducer 61 (Cyr61) is an extracellular matrix protein involved in the transduction of growth factor and hormone signaling that is frequently altered in expression in several types of cancers. In prostate cancer (PCa), Cyr61 is highly expressed in organ-confined disease. Further, Cyr61 expression levels are associated with a lower risk of disease recurrence, and can be quantitatively measured in the serum. Considered together, these results indicate that Cyr61 is a potential and clinically useful tissue, as well as serum-based biomarker for differentiating lethal and non-lethal PCa.

References

Jul 1, 1990·Molecular and Cellular Biology·T P O'BrienL F Lau
Dec 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·D PennicaA J Levine
Apr 12, 2001·The Journal of Biological Chemistry·D XieH P Koeffler
Oct 13, 2001·The Journal of Biological Chemistry·X TongH P Koeffler
Jan 17, 2002·The Journal of Urology·Gerald W HullPeter T Scardino
Apr 3, 2002·JAMA : the Journal of the American Medical Association·Mark A RubinArul M Chinnaiyan
May 29, 2002·Proceedings of the National Academy of Sciences of the United States of America·Kulkarni PrakashRobert H Getzenberg
Jan 9, 2004·Journal of Biomolecular Screening·Shinji SakamotoYoshiyuki Kakehi
Mar 26, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Dong XieH Phillip Koeffler
Apr 8, 2004·Neoplasia : an International Journal for Oncology Research·Daniel R RhodesArul M Chinnaiyan
May 14, 2004·Neoplasia : an International Journal for Oncology Research·Shanta M MesserliChing-Hsuan Tung
Aug 25, 2004·American Journal of Clinical Pathology·Zhong JiangXiming J Yang
Oct 9, 2004·The Journal of Biological Chemistry·Wenwen ChienH Phillip Koeffler
Mar 2, 2005·Journal of the American College of Surgeons·Shane E HollowayJason B Fleming
Mar 17, 2005·Frontiers in Bioscience : a Journal and Virtual Library·Anne-Marie BleauBernard Perbal
Jun 9, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mark A RubinJan-Erik Johansson
Aug 24, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ming-Tsai LinMin-Liang Kuo
Dec 16, 2006·Journal of Cellular Biochemistry·Ying Chen, Xiao-Yan Du
Jan 11, 2007·Journal of Clinical Pathology·P A Humphrey
Aug 19, 2007·The International Journal of Biochemistry & Cell Biology·Ping FengEe Chee Ren
Feb 20, 2008·Prostate Cancer and Prostatic Diseases·D KaranD Lubaroff
Sep 9, 2008·The International Journal of Biochemistry & Cell Biology·Chih-Chiun Chen, Lester F Lau
Jul 9, 2009·Molecular Cancer Research : MCR·Carrie A FranzenLester F Lau
Feb 23, 2010·The Journal of Urology·Katherine B D'AntonioRobert H Getzenberg
Dec 9, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Katherine B D'AntonioRobert H Getzenberg

❮ Previous
Next ❯

Citations

Apr 25, 2014·Asian Journal of Andrology·Chang-Ming Lin, Chao-Zhao Liang
Aug 12, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Weidong ShiZhiqiang Meng
Dec 24, 2015·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Sanghoon HanDong Bok Shin
Dec 17, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Gang ChengJianning Zhang
Oct 16, 2016·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Y F SongQ Lin
Aug 11, 2017·Therapeutic Advances in Medical Oncology·Naoki TeradaEmmanuel S Antonarakis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.