Cystadenoma of the palate: immunohistochemistry of mucins

Pathology International
Kimihide KusafukaToru Kameya

Abstract

Cystadenoma is a relatively rare benign epithelial tumor of the salivary glands, and described herein is an additional case. A 51-year-old Japanese man had noticed a mass of the left hard palate 25 years previously. Macroscopically, the resected specimen was a multicystic lesion. Histologically, the tumor was composed of bilayered columnar epithelium with cystic change and partial solid growth of glandular structures with clear cells. The tumor cells had mild cellular atypia, but the tumor lacked papillary growth and a fibrous capsule. Immunohistochemistry was positive for cytokeratins, epithelial membrane antigen, MUC1, MUC4 and MUC6, but negative for myoepithelial markers, MUC2, MUC5AC and MUC5B. Such MUC expression patterns suggested that cystadenoma occurs from excretory ducts.

References

Dec 1, 1978·Oral Surgery, Oral Medicine, and Oral Pathology·S M KerpelH Lumerman
Sep 1, 1988·Oral Surgery, Oral Medicine, and Oral Pathology·C A WaldronD R Gnepp
Jan 1, 1995·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·J B Alexis, V Dembrow
Jul 1, 1997·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·J G GuccionN Saini
Jul 29, 2003·The American Journal of Surgical Pathology·Roderick H W SimpsonLeonor David
Mar 1, 1954·Oral Surgery, Oral Medicine, and Oral Pathology·S G CASTIGLIANO, L GOLD
Dec 1, 1958·American Journal of Surgery·E M COLLINS
Jan 1, 1959·Cancer·R L BROWNH S GIRARDEAU
Apr 1, 1960·Oral Surgery, Oral Medicine, and Oral Pathology·A P CHAUDHRYD F MITCHELL
Nov 18, 2003·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Sebastian MannweilerCord Langner
Jul 25, 2006·The American Journal of Surgical Pathology·Ilan WeinrebBayardo Perez-Ordoñez

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Citations

Mar 15, 2015·The Bulletin of Tokyo Dental College·Takeshi OndaTakahiko Shibahara
May 9, 2018·The American Journal of Surgical Pathology·Abbas AgaimyFlorian Haller
Mar 17, 2020·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Eduardo Morato de OliveiraMaria Cássia Ferreira de Aguiar

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