PMID: 9651412Jul 4, 1998Paper

Cystic fibrosis newborn screening: impact on reproductive behavior and implications for genetic counseling

Pediatrics
E H MischlerP Farrell

Abstract

To evaluate the impact of newborn screening for cystic fibrosis (CF) on the reproductive knowledge and behavior of CF families and to determine if heterozygote detection with the immunoreactive trypsinogen (IRT) method in conjunction with DNA analysis (IRT/DNA) influences knowledge and attitudes about reproduction in false-positive families. The Wisconsin CF Neonatal Screening Project investigated 650 340 infants from 1985 to 1994 in a comprehensive randomized controlled trial to study both benefits and risks of newborn screening and to determine if early diagnosis would improve the prognosis of children with CF. Assessments of reproductive knowledge, attitudes, and behaviors of 135 families of children diagnosed as having CF in both the early treatment group and control groups were made 3 months after diagnosis using a questionnaire which was completed by 100 families. The same questionnaire was administered 1 year later to evaluate retention of information. It was completed by 71 families. A follow-up assessment tool was also administered in 1994 and responses obtained from 73 families. Knowledge, attitudes, and behavior among false-positive families were also assessed at the time of the sweat test in 206 families who experie...Continue Reading

References

Jan 1, 1979·American Journal of Medical Genetics·A Lippman-Hand, F C Fraser
Sep 12, 1991·The New England Journal of Medicine·N A Holtzman
Nov 1, 1990·Archives of Disease in Childhood·C Boland, N L Thompson
Oct 1, 1987·Clinical Genetics·J E Dankert-RoelseL P ten Kate
Jul 1, 1995·Journal of Medical Genetics·M E BalnavesS Forrest
Jul 1, 1995·Thorax·P D Phelan
May 1, 1996·Prenatal Diagnosis·R A DohertyJ E Haddow
Jul 11, 1997·American Journal of Medical Genetics·J H Fanos

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Citations

Jan 3, 2013·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Hannah M BakerAudrey Tluczek
Dec 6, 2003·The Journal of Pediatrics·Michael H Farrell, Philip M Farrell
Nov 25, 2003·Paediatric Respiratory Reviews·Carlo Castellani
Nov 25, 2003·Paediatric Respiratory Reviews·Evelyn P Parsons, Donald M Bradley
Mar 12, 2009·European Journal of Human Genetics : EJHG·Pascal BorryUNKNOWN Public and Professional Policy Committee (PPPC) of the European Society of Human Genetics (ESHG)
Jun 1, 2010·European Journal of Human Genetics : EJHG·Belinda J McClarenDavid J Amor
Nov 11, 2011·European Journal of Human Genetics : EJHG·Lainie Friedman Ross
Mar 2, 2012·European Journal of Human Genetics : EJHG·Yvonne Bombard, Fiona A Miller
Feb 18, 2005·Nature Reviews. Genetics·Nancy S Green, Kenneth A Pass
Oct 18, 2005·Genetic Testing·Erin LagoePeter T Rowley
Jun 14, 2003·Current Opinion in Pediatrics·Jeffrey S WagenerFrank J Accurso
Oct 24, 2002·Current Opinion in Pulmonary Medicine·Benjamin Wilfond, L S Rothenberg
Nov 21, 2001·Genetics in Medicine : Official Journal of the American College of Medical Genetics·P G WheelerD W Bianchi
May 7, 2011·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Beth KladnyLakshmanan Krishnamurti
Nov 21, 2007·Current Opinion in Pediatrics·Alex R Kemper, Melissa A Wake
Aug 24, 2006·Journal of Paediatrics and Child Health·Sharon LewisJohn Massie
Oct 9, 1998·BMJ : British Medical Journal·P M Farrell
Feb 24, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·T DuddingG Turner
Sep 1, 2009·Annual Review of Genomics and Human Genetics·Jill Waalen, Ernest Beutler
Jul 18, 2002·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·L F Ross
Oct 3, 2003·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society, UNKNOWN European Respiratory Society
Sep 21, 2010·Qualitative Health Research·Audrey TluczekLaura Cavanagh
Dec 9, 2008·American Journal of Public Health·Fiona Alice MillerRobin Z Hayeems
Jun 19, 2013·Journal of the American Medical Informatics Association : JAMIA·Kimberly ShoenbillEneida A Mendonca
Feb 10, 2016·Clinics in Chest Medicine·John Brewington, J P Clancy
Mar 20, 2014·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Audrey Tluczek, Jane M De Luca
Aug 23, 2008·The Journal of Pediatrics·Lainie Friedman Ross
Nov 14, 2015·European Journal of Medical Genetics·D F Vears, S A Metcalfe
May 29, 2013·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Toni TorresaniUNKNOWN Swiss CF Screening Group
Feb 2, 2008·Prenatal Diagnosis·Virginie ScotetClaude Férec
Jan 11, 2013·American Journal of Medical Genetics. Part a·Louise ChristieMichael Field
Aug 11, 2015·Pediatric Pulmonology·Katelyn Parker-McGillHara Levy
Oct 6, 2005·The Journal of Pediatrics·Benjamin S WilfondNorman Fost
Oct 6, 2005·The Journal of Pediatrics·James Price Dillard, Audrey Tluczek
Sep 13, 2014·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·C P B van der PloegUNKNOWN CHOPIN study group

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