PMID: 589855Dec 1, 1977

Cystinuria and mental deficiency

Clinical Genetics
R J GoldD P Gold

Abstract

Several studies have shown that the incidence of cystinuria in mentally retarded populations is higher than it is in the general population. The present study found that a group of cystinurics did not differ significantly in their intelligence from their normal siblings or intelligence test norms. Since cystinuria is a heterogeneous disease, the findings of the present study could be reconciled with previous findings by supposing that only certain genotypes for cystinuria lead to mental retardation.

References

Oct 8, 1970·The New England Journal of Medicine·C R ScriverL Dallaire
Mar 1, 1966·The Journal of Clinical Investigation·L E ROSENBERGS SEGAL
Oct 1, 1962·Archives of Disease in Childhood·N A CARSON, D W NEILL
May 20, 1965·The New England Journal of Medicine·M L EFRON

Citations

Jul 13, 2007·European Journal of Human Genetics : EJHG·Ruti Parvari, Eli Hershkovitz
Aug 1, 1980·Journal of Neurochemistry·S M HwangS SEGAL

Related Concepts

Cystinuria
Profound Mental Retardation

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