PMID: 9550353Jan 1, 1996Paper

Cytidin-5'-diphosphocholine enhances the effect of part-time occlusion in amblyopia

Documenta Ophthalmologica. Advances in Ophthalmology
E C CamposV Porciatti

Abstract

Cytidin-5'-diphosphocholine (CDP-choline) has been shown to improve visual acuity (VA), Contrast Sensitivity and Visual Evoked Responses at least temporarily, in amblyopic patients beyond the plastic period of the visual system. In this paper results are presented of a study conducted on forty-five patients with amblyopia in one eye, aged 5-9 years and followed for one year. Of them, 15 (Group A) were treated with CDP-choline (500 mg daily for 10 days every six months); 15 (Group B) were treated with CDP-choline plus one hour of occlusion daily; 15 (Group C) were treated with one hour of occlusion daily. The final VA values were statistically different from the initial ones, for all three groups. Eleven of the Group A patients showed an improvement in VA after the first treatment; a gradual deterioration took place in 6 patients at the end of the fourth month; VA further improved in 9 patients after the second treatment. At the end of the year, VA was higher than at the beginning in 12 of the 15 patients. Group B had an improvement of VA in 13 patients, starting 10 days from the beginning of treatment. This improvement continued throughout the observation period. Group C had an improvement after one month, which continued for 8...Continue Reading

References

Jan 15, 1985·American Journal of Ophthalmology·E C Campos, R Gulli
Jul 1, 1995·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·I GottlobR D Reinecke
May 1, 1995·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·E C CamposV Porciatti
Jul 1, 1995·Survey of Ophthalmology·E Campos

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Citations

Dec 4, 2015·International Journal of Molecular Sciences·Gloria RobertiFrancesco Oddone
Dec 14, 2019·Korean Journal of Ophthalmology : KJO·Shin Hae Park
Dec 13, 2019·Journal of Refractive Surgery·Esat CinarGökhan Erbakan
Feb 2, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Eleni PapageorgiouIrene Gottlob
Jun 9, 2006·Strabismus·Emilio C Campos, Michela Fresina
Jul 20, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Michela FresinaEmilio C Campos
Jan 15, 2014·Journal of Pediatric Ophthalmology and Strabismus·Nicola PescosolidoStefano Fazio
May 11, 2020·International Ophthalmology·Esat CinarGökhan Erbakan
Jun 27, 2019·Progress in Retinal and Eye Research·Muneeb A FaiqKevin C Chan
Mar 8, 2005·Survey of Ophthalmology·Kurt Simons

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