PMID: 9537049Jan 1, 1980Paper

Cytochemistry of human T-cell subpopulations

Scandinavian Journal of Immunology
A BevanJ C Cawley

Abstract

Acid phosphatase and esterase cytochemistry performed on purified normal human T-cell populations showed that both methods produced distinctive localized dot patterns of reactivity in 60-70% of cells. By examination of rosette preparations formed with ox erythrocytes coated with IgM (EAM), with IgG (EAG), or anti-human kappa and lambda light chains, it was shown that this pattern of reactivity was largely restricted to small T lymphocytes possessing receptors for the Fc of IgM (T mu cells). In addition, both B lymphocytes and T cells with receptors for the Fc of IgG (T gamma cells) were larger lymphocytes with more abundant cytoplasm and usually displayed scattered granular acid phosphatase activity; in esterase preparations both cell types were either negative or possessed similar scattered granular positivity. As compared with T mu cells, T gamma cells were seen to form loose spontaneous rosettes with sheep erythrocytes. Combined esterase and acid phosphatase staining showed that both enzyme activities in the T mu cells are localized in the same area, and ultrastructural acid phosphatase cytochemistry established that this was in distinctive lysosomal structures. T mu staining by both esterase and acid phosphatase cytochemist...Continue Reading

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Citations

Jul 1, 1982·Journal of Reproductive Immunology·O LassilaP Toivanen
Feb 26, 2000·Veterinary Immunology and Immunopathology·L Petrie-Hanson, A J Ainsworth
Jul 9, 1983·British Medical Journal·T J HamblinD B Jones
Sep 13, 2005·Developmental and Comparative Immunology·Eva BengténMelanie Wilson
Nov 1, 1982·Arthritis and Rheumatism·Y T KonttinenO Wegelius
Oct 1, 1980·Immunology Today·J C Cawley, G F Burns
Jan 1, 1990·Stain Technology·L Kass
Jun 1, 1982·American Journal of Hematology·R D Barr, C A Stevens
Jan 1, 1989·The American Journal of Drug and Alcohol Abuse·M R LiepmanA M Begin
May 1, 1983·Scandinavian Journal of Haematology·A Crockard, D Catovsky
Jun 1, 1982·Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section C, Immunology·O Lassila, A Alanen
Oct 1, 1985·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·R DeneckeG Trautwein
Jan 1, 1981·Clinical and Laboratory Haematology·D L BarnardJ L Cawley
Feb 1, 1984·Scandinavian Journal of Haematology·A HirtH P Wagner
May 1, 1983·Scandinavian Journal of Haematology·R D BarrG R Honig

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