Oct 1, 1989

Cytochrome P-450 monooxygenases in insects

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
M J Ronis, E HODGSON

Abstract

1. The insect monooxygenase system is involved in the oxidative metabolism of both endogenous and exogenous substrates. 2. Monooxygenases appear to be important in insect growth and development, in adaptation to multiple food plants in phytophagous insects and in pesticide resistance. 3. The genetics, purification and properties of cytochrome P-450 isozymes of the house fly (Musca domestica) are discussed in relation to their role in resistance to xenobiotics. 4. Induction of insect cytochrome P-450 isozymes is discussed in comparison to induction in mammals and with reference to polyphagy.

  • References9
  • Citations43

References

Mentioned in this Paper

phm
Microsomes
Cytochrome P450
Cell Respiration
Musca domestica (invertebrate)
Cytochrome P-450 Oxygenase
Xenobiotics
Pesticide Resistance
Purification Aspects
House fly allergenic extract

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