PMID: 9434105Jan 20, 1998Paper

Cytochromes c-552 from two strains of the hydrogenotrophic bacterium Alcaligenes eutrophus are sequence homologs of the cytochromes c8 from the denitrifying pseudomonads

Biochimica Et Biophysica Acta
K KlarskovJ J Van Beeumen

Abstract

Soluble cytochromes c-552 were purified from two strains of the hydrogenothrophic species Alcaligenes eutrophus and their amino acid sequences determined. The two cytochromes were found to have 5 differences out of a total of 89 residues. The proteins are clearly related to the cytochromes c8 (formerly called Pseudomonas cytochromes c-551), but require a single residue insertion after the methionine sixth heme ligand relative to the Pseudomonas aeruginosa protein. The consensus residues Trp56 and Trp77, characteristic for the c8 family, are also present in the Alcaligenes proteins. Overall, the Alcaligenes cytochromes are only 43% identical to the Pseudomonas proteins which average 68% identity to one another. They are also only 45% identical to cytochrome c8 from Hydrogenobacter thermophilus, another hydrogenothrophic species, which indicates that the hydrogen utilizing bacteria are not more closely related to one another than they are to other species. The finding of cytochrome c8 in Alcaligenes eutrophus completes the recent characterization of a cytochrome cd1-nitrite reductase from this bacterial species and suggests the existence of the same denitrification pathway as in Pseudomonas where these two proteins are reaction p...Continue Reading

References

Aug 13, 1976·Biochimica Et Biophysica Acta·I Probst, H G Schlegel
Oct 1, 1992·Journal of Bacteriology·C KortlükeB Friedrich
Mar 20, 1992·Journal of Molecular Biology·S Pascarella, P Argos
May 23, 1991·Biochimica Et Biophysica Acta·R P Ambler
Jun 1, 1987·Microbiological Reviews·C R Woese
Jan 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·T E MeyerM D Kamen
Mar 1, 1973·The Biochemical Journal·R P Ambler, M Wynn
Jan 1, 1981·Annual Review of Microbiology·B Bowien, H G Schlegel
Jul 1, 1995·Current Microbiology·T FujiwaraY Fukumori
Jan 1, 1993·Annual Review of Microbiology·B Friedrich, E Schwartz
Sep 1, 1993·Journal of Bacteriology·R A SiddiquiB Friedrich
Feb 1, 1997·Applied and Environmental Microbiology·E ReesB Friedrich

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