PMID: 9435880Jan 1, 1997Paper

Cytogenetic biomonitoring in traffic police workers: micronucleus test in peripheral blood lymphocytes

Environmental and Molecular Mutagenesis
C BolognesiA Abbondandolo

Abstract

Atmospheric pollution represents a relevant environmental hazard which has been associated with considerable excess mortality, morbidity, and increased rates of respiratory diseases in humans. To date, more than 3,000 environmental chemical compounds have been identified in the ambient atmosphere, including a variety of mutagenic and/or carcinogenic agents, such as polycyclic aromatic hydrocarbons (PAHs), aromatic amines, and heterocyclic compounds. Positive associations between cytogenetic markers and airborne levels of PAHs have been reported by experimental and human studies. Traffic has been implicated as the major determinant for the concentration of PAHs and, therefore, for the genotoxic activity of urban air. A biomonitoring study has been conducted in 82 italian traffic police workers exposed to air pollutants and 34 control subjects (matched by age, gender, and smoking habits) not exposed to traffic pollutants. The aim of this study was to assess the cytogenetic effects, such as micronucleus frequency in peripheral blood lymphocytes, and to estimate the association with individual exposure to PAH. Statistical analysis of the frequency of micronuclei in binucleated cells showed higher mean levels in referent subjects (4...Continue Reading

Citations

Mar 25, 2011·Environmental Health and Preventive Medicine·Chuancheng WuKanehisa Morimoto
Jan 30, 2002·Mutation Research·Francesca MaffeiPatrizia Hrelia
Feb 15, 2001·Occupational and Environmental Medicine·R CrebelliA Carere
Nov 1, 2012·Indian Journal of Occupational and Environmental Medicine·Ajanta Halder, Madhusnata De
Mar 20, 2012·International Journal of Hygiene and Environmental Health·Shigeo IshikawaAkira Fukao
Jun 26, 2007·Toxicology Letters·Bozena NovotnaRadim J Sram
Feb 28, 2007·The Science of the Total Environment·R BonoM Bugiani
May 19, 2009·Environmental and Molecular Mutagenesis·Delia CavalloSergio Iavicoli
Nov 26, 2009·Journal of Applied Toxicology : JAT·Vilena KasubaZorana Kljaković-Gaspić
Mar 18, 2005·Genetika·V A Timoshevski, S A Nazarenko
Nov 7, 2016·Environmental Science and Pollution Research International·C Martínez-ValenzuelaR Longoria-Espinoza

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