Cytogenetic characterization of a fibrous hamartoma of infancy with complex translocations

Cancer Genetics and Cytogenetics
Elisa TassanoCristina Morerio

Abstract

Fibrous hamartoma of infancy is a rare pediatric superficial soft tissue lesion. The diagnosis depends on microscopic examination. Conventional cytogenetic analysis has been reported in only two previous cases, which showed apparently balanced translocations with involvement of different chromosomes. In the present study, we used multicolor fluorescence in situ hybridization to characterize a case of fibrous hamartoma of infancy that had arisen in an unusual location. This molecular analysis revealed complex structural rearrangements involving chromosomes 1, 2, 4, and 17.

References

Mar 24, 2004·Cancer Genetics and Cytogenetics·Kerry BernalJulia A Bridge
Sep 15, 2004·Virchows Archiv : an International Journal of Pathology·Nicolas SirventFlorence Pedeutour
Mar 30, 2005·Archives of Pathology & Laboratory Medicine·Renuka LakshminarayananJeanna Welborn
Nov 23, 2006·Cancer Genetics and Cytogenetics·Anne-Laure RougemontJean-Christophe Fournet
Nov 27, 2007·Cancer Genetics and Cytogenetics·Barton KenneyEduardo Zambrano
Jul 15, 2009·Cancer Genetics and Cytogenetics·Amin MaghariMeera Hameed

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Citations

Sep 16, 2016·The American Journal of Surgical Pathology·Jason Y ParkDinesh Rakheja
Dec 12, 2012·Journal of Lower Genital Tract Disease·Maryam MonajemzadehShanyandokht Taleb
Nov 11, 2019·Virchows Archiv : an International Journal of Pathology·Ivy John, Karen J Fritchie
Dec 14, 2011·Advances in Anatomic Pathology·Khin ThwayNeil J Sebire
Jan 7, 2017·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Alyaa Al-IbraheemiAndrew L Folpe
Jan 1, 2021·Actas dermo-sifiliográficas·L Martos-CabreraM Llamas-Velasco
May 11, 2021·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Jonathan C SlackKyle C Kurek
Jun 6, 2021·Actas dermo-sifiliográficas·L Martos-CabreraM Llamas-Velasco

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