Cytogenetic instability, predominantly involving chromosome 1, is characteristic of elastofibroma

Cancer Genetics and Cytogenetics
E N McCombJ A Bridge

Abstract

Elastofibroma, an unusual pseudotumor composed of excessive collagen and abnormal elastic fibers, has rarely been subjected to cytogenetic analysis. Only two cases have been previously defined, both of which demonstrated nonclonal abnormalities. In the present study, three cases of elastofibroma were cytogenetically analyzed. Abnormalities of the short arm of chromosome 1 were seen in all three cases (either clonally or as the most frequently involved region among nonclonal aberrations). In addition, a translocation involving chromosomes 8 and 12 was detected as a clonal rearrangement in one of the three cases. The observation of clonal abnormalities in elastofibroma suggests that this lesion may represent a neoplastic rather than a reactive process.

References

Jul 1, 1979·Arthritis and Rheumatism·P Prete, R P Thorne
May 1, 1992·Cancer Genetics and Cytogenetics·A DembinskiA A Sandberg
Apr 1, 1990·Cancer Genetics and Cytogenetics·C U DietrichR Hochsattel
Mar 1, 1985·The American Journal of Surgical Pathology·M EnjojiK Sueyoshi
Sep 1, 1988·Cancer Genetics and Cytogenetics·I KarlssonF Mitelman
Jan 1, 1974·Cancer·J M MirraO H Järvi
Jan 1, 1969·Cancer·O H JärviV T Vaissalo
Sep 1, 1974·The British Journal of Radiology·G P Deutsch
Jul 1, 1974·The British Journal of Surgery·J C McGregor, S S Rao
Sep 1, 1984·Southern Medical Journal·D L CrossD N Kulund
Aug 16, 1994·Proceedings of the National Academy of Sciences of the United States of America·R PrasadE Canaani
Jul 1, 1993·Cancer Genetics and Cytogenetics·M TarkkanenS Knuutila
Jun 1, 1996·Cancer Genetics and Cytogenetics·E N McCombJ A Bridge
Apr 1, 1997·Nature Genetics·F MitelmanB Johansson
Jun 5, 1998·Arkhiv patologii·G A Galil-OglyG M Korobeĭnikova
Jun 1, 1999·AJR. American Journal of Roentgenology·C Wakeley
Sep 15, 2000·Annals of Plastic Surgery·R YavuzerO Süer
Jul 1, 1974·Journal of Clinical Pathology·D H Mackenzie
Jun 15, 2007·La Presse médicale·Sébastien Le GoudevezeRené Jancovici

❮ Previous
Next ❯

Citations

Sep 1, 2005·Virchows Archiv : an International Journal of Pathology·Masanori Hisaoka, Hiroshi Hashimoto
Apr 29, 2010·Surgery Today·Oguz KokselAli Ozdulger
Mar 20, 2010·Head and Neck Pathology·Konstantinos I TosiosIoannis G Koutlas
Apr 18, 2003·Cancer Genetics and Cytogenetics·Marilu NelsonJulia A Bridge
Dec 31, 2003·Journal of the American Academy of Dermatology·Satoko ShimizuKikuo Tsuchiya
Aug 5, 2014·The Annals of Thoracic Surgery·Tevfik İlker AkçamHaluk Akın
Jan 10, 2012·Annales de dermatologie et de vénéréologie·O HocarM Bagot
Apr 29, 2011·Journal of Shoulder and Elbow Surgery·Jun NishioMasatoshi Naito
Sep 21, 2010·Journal of Shoulder and Elbow Surgery·Hiroshi HatanoTetsuo Hotta
Jun 29, 2010·Journal of Cutaneous Pathology·Cassiano Francisco Weege NonakaLeão Pereira Pinto
Sep 26, 2006·The Annals of Thoracic Surgery·Clemens SchafmayerJuergen Tepel
Jan 17, 2008·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Ritu ManchanduFaizan Alawi
Jun 27, 2003·Advances in Anatomic Pathology·G Petur NielsenAndrew E Rosenberg
Jan 10, 2009·Virchows Archiv : an International Journal of Pathology·Keita KaiOsamu Tokunaga
Apr 28, 2010·Virchows Archiv : an International Journal of Pathology·Juan Luis García HernándezAgustín Bullón
Feb 13, 2004·International Journal of Impotence Research·J P MulhallT V Shankey
Apr 12, 2007·Diagnostic Cytopathology·Jan Janzen
Feb 14, 2007·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Banu Dogan GunSukru Oguz Ozdamar
Oct 16, 2012·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Giuseppe MagliuloMassimo Re
Dec 9, 2020·ANZ Journal of Surgery·Mutlu Sahin, Vahit O Gul

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Virchows Archiv : an International Journal of Pathology
Masanori Hisaoka, Hiroshi Hashimoto
Journal of the American Academy of Dermatology
Satoko ShimizuKikuo Tsuchiya
Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Ritu ManchanduFaizan Alawi
© 2021 Meta ULC. All rights reserved