PMID: 6962753Dec 1, 1982Paper

Cytogenetic studies of acute promyelocytic leukemia

Cancer Genetics and Cytogenetics
P H FitzgeraldM E Beard

Abstract

Translocation t(15;17) is reported in bone marrow cells from six of seven patients with active acute promyelocytic leukemia (APL). One patient who showed t(15;17) at final relapse did not show it in directly prepared or cultured cells taken from a previous relapse. Bone marrow samples from two patients showed only cells with a normal karyotype in the direct preparation, whereas more than 60% of cells cultured for 24 hr showed t(15;17). R-Banding, G-banding, and an attempt at high-resolution banding indicated the break points t(15;17)(q24;21) for one of our patients.

References

Jul 12, 1978·Human Genetics·J M ScheresF J Rutten
Feb 1, 1979·Cancer·H Van Den BergheG Sokal
Jan 1, 1980·British Journal of Haematology·J M BennettC Sultan
Jul 16, 1981·The New England Journal of Medicine·J J YunisK Ensrud
Feb 15, 1981·International Journal of Cancer. Journal International Du Cancer·J F FraserM E Beard

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Citations

Jan 1, 1983·Cancer Genetics and Cytogenetics·P H FitzgeraldM E Beard
May 1, 1985·Cancer Genetics and Cytogenetics·Y SonodaT Takino
Jan 15, 1986·Cancer Genetics and Cytogenetics·M De Braekeleer, C C Lin
Jun 1, 1988·Australian and New Zealand Journal of Medicine·M E Beard, P H Fitzgerald
Aug 1, 1984·Scandinavian Journal of Haematology·G AlimenaF Mandelli
Jun 1, 1986·British Journal of Haematology·E C PearsonF G Hayhoe

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