PMID: 2452760Jan 1, 1987

Cytokeratins in certain endothelial and smooth muscle cells of two taxonomically distant vertebrate species, Xenopus laevis and man

Differentiation; Research in Biological Diversity
L JahnW W Franke


Using immunolocalization techniques, electron microscopy, and gel electrophoresis combined with immunoblotting, we have noted remarkable interspecies differences in the expression of cytokeratins in certain nonepithelial cells. In the present study we describe, in two taxonomically distant vertebrate species, the African clawed toad Xenopus laevis and man, endothelial and smooth muscle cells which express cytokeratin intermediate filaments (IFs), in addition to vimentin and/or desmin IFs. In Xenopus, all endothelia seem to produce both vimentin and cytokeratin IFs. As well, certain smooth muscle bundles located in the periphery of the walls of the esophagus and the urinary bladder produce small amounts of cytokeratin IFs in addition to IFs containing vimentin or desmin or both. The amphibian equivalents of human cytokeratins 8 and 18 have been identified in these nonepithelial tissues. In human endothelial cells, immunocytochemical reactions with certain cytokeratin antibodies are restricted to a rare subset of blood vessels. Vessels of this type were first noted in synovial and submucosal tissues, but also occur in some other locations. Cytokeratins have also been detected in certain groups of smooth muscles, such as those pre...Continue Reading


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Jan 1, 1992·Journal of Cancer Research and Clinical Oncology·Y UedaA Roessner
May 1, 1995·Histochemistry and Cell Biology·A M RickenP R Huber
Jan 1, 1990·Virchows Archiv. A, Pathological Anatomy and Histopathology·C DoglioniG Viale
Oct 1, 1989·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·A KnedlerR G Ham
Feb 1, 1993·Comparative Biochemistry and Physiology. Comparative Physiology·R Mineau-HanschkeD Shepro
Jan 1, 1991·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·A B DodgeD Shepro
Sep 1, 1995·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·K PantelM W Köllermann
Jan 30, 2004·Oral Oncology·Ojaswini S UpasaniAvinash N Bhisey
Jan 1, 1992·Acta histochemica·M KasperB Lane
Jan 1, 1996·Progress in Histochemistry and Cytochemistry·K PantelG Schlimok
Nov 5, 1997·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·M ImbodenS Vriz
Aug 8, 1998·Progress in Retinal and Eye Research·T Kivelä, M Uusitalo
Dec 1, 1993·The Journal of Cell Biology·V C CordesW W Franke
Nov 11, 1999·The American Journal of Surgical Pathology·O Ben-IzhakA Hoffman
Apr 24, 2004·The American Journal of Surgical Pathology·Kimberly H AllisonBrian P Rubin
Nov 1, 1990·Histopathology·R J Fitzmaurice, J McClure
Dec 1, 1991·Histopathology·W Y TsangC D Fletcher
Nov 1, 1994·Histopathology·R J PrescottN Y Haboubi
Sep 15, 1992·European Journal of Biochemistry·J V SmallL E Thornell
Mar 1, 1997·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M LuomanenR P Happonen
Jun 1, 1994·Annals of the Rheumatic Diseases·A A BorgD L Mattey
Feb 1, 1992·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·S C HeffelfingerG J Darlington


Dec 1, 1978·The Journal of Cell Biology·R K LiemM L Shelanski
Jan 1, 1979·Differentiation; Research in Biological Diversity·E SchmidW W Franke
Jun 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·T T SunH Green
Jan 1, 1978·Cell·R O Hynes, A T Destree
Jan 1, 1979·Experimental Cell Research·W W FrankeM Osborn
Jun 1, 1979·The Journal of Cell Biology·W W FrankeK Weber
Mar 1, 1976·The Journal of Cell Biology·P Cooke
Jan 1, 1985·Virchows Archiv. A, Pathological Anatomy and Histopathology·J von OverbeckP U Heitz
Jan 1, 1985·Virchows Archiv. A, Pathological Anatomy and Histopathology·P StosiekM Kasper
Oct 1, 1985·The Journal of Cell Biology·P CowinW W Franke
Oct 1, 1985·Oral Surgery, Oral Medicine, and Oral Pathology·G L EllisF M Enzinger
Jan 1, 1985·Annals of the New York Academy of Sciences·R A QuinlanW W Franke
Jan 1, 1985·Annals of the New York Academy of Sciences·M A Glicksman, M Willard
Jan 1, 1986·Differentiation; Research in Biological Diversity·A SématM Darmon
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·J K Franz, W W Franke
Jun 15, 1987·Cancer·M LeaderH Kristin
May 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·M C FrankoD C Gajdusek
May 1, 1987·The American Journal of Surgical Pathology·G L EllisV J Hyams
Jan 1, 1987·Ultrastructural Pathology·F N Ghadially
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·W W FrankeC Stähli
May 1, 1987·Histopathology·D C BrownD Y Mason
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·M LeaderK Henry
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Feb 1, 1987·European Journal of Cancer & Clinical Oncology·M KasperU Karsten
Jan 1, 1985·Virchows Archiv. A, Pathological Anatomy and Histopathology·Y NakazatoK Suzuki
Jun 1, 1985·The Journal of Pathology·C E du Boulay

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