Cytokine and nitric oxide production following severe envenomation

Current Drug Targets. Inflammation and Allergy
V L Petricevich

Abstract

Venom is a complex mixture of many substances such as toxins, enzymes, growth factor activators, and inhibitors are particularly responsible for the deleterious effects of cells. These constituents interact in the body with a large number of proteins and receptors, and this interaction determines the eventual inflammatory effect of the compounds. Envenomation by bees, scorpions, snakes, spiders and wasps involves the activation of the inflammatory response with the release and activation of pro-inflammatory cytokines and other mediators, such as nitric oxide. Recently, a battery of cytokines produced by activated T cells or macrophages have been added to in envenomations. Cytokines are important for the interactions between cells in the immune and inflammatory responses. Although the pathophysiology of envenomation is not fully understood, venom and immune responses are known to trigger the release of cytokines and nitric oxide. The cytokines initiate a cascade of events that lead to illness behaviors such as fever, anorexia, and, as well as a host of physiologic events such as activation of vasodilation, hypotension and increased nitric oxide production. Accumulating evidence indicates that these cytokines play important roles...Continue Reading

Citations

Aug 4, 2005·Aesthetic Plastic Surgery·Yusuf Kenan Coban
May 7, 2011·Inflammation·Sonia Adi-BessalemFatima Laraba-Djebari
Apr 2, 2013·Journal of Ethnopharmacology·Niramai FangkrathokBungorn Sripanidkulchai
Mar 10, 2012·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·R S FerreiraB Barraviera
Mar 20, 2013·BioMed Research International·Victor Corasolla CarregariSergio Marangoni
Feb 21, 2006·Mediators of Inflammation·Anselmo Hernández CruzVera L Petricevich
Aug 21, 2013·Journal of Natural Medicines·Niramai FangkrathokBungorn Sripanidkulchai
Jul 8, 2008·Mediators of Inflammation·A Hernández CruzV L Petricevich
Dec 17, 2011·Mediators of Inflammation·A Hernández CruzV L Petricevich
Mar 20, 2010·Mediators of Inflammation·Vera L Petricevich
Dec 30, 2014·Neuroscience Letters·Iva Tereza Van FragaJuliana Carvalho-Tavares
Jul 10, 2010·Toxicon : Official Journal of the International Society on Toxinology·Katia C BarbaroMarcelo L Santoro
Aug 12, 2009·Neuroscience Letters·Ana Leonor A NencioniValquiria A C Dorce
May 27, 2009·Toxicon : Official Journal of the International Society on Toxinology·Nuzha A Abdoon, Amal J Fatani
Nov 4, 2008·Toxicon : Official Journal of the International Society on Toxinology·Lídia M YshiiSoraia K P Costa
Aug 7, 2007·Toxicon : Official Journal of the International Society on Toxinology·Vera L PetricevichLourival D Possani
Apr 4, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Marcus V AndradeJosé Renan Cunha-Melo
Feb 10, 2006·Toxicon : Official Journal of the International Society on Toxinology·Abdel-Haleem A Abdel-HaleemZaghloul T Mohamed
Mar 4, 2014·Toxicon : Official Journal of the International Society on Toxinology·Vanesa Ramírez-BelloGina D'Suze
Sep 29, 2005·Biochemical and Biophysical Research Communications·Tianbao ChenChris Shaw
Jul 21, 2011·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Mohamed A Abdel-RahmanPeter N Strong
Feb 9, 2012·Toxicon : Official Journal of the International Society on Toxinology·M BarriosB Guerrero
Mar 13, 2012·Toxicon : Official Journal of the International Society on Toxinology·Núbia Braga PereiraLuciana Moro
Sep 1, 2016·Toxicon : Official Journal of the International Society on Toxinology·Peter TaylorBelsy Guerrero
Oct 30, 2016·Toxicon : Official Journal of the International Society on Toxinology·K N SanthoshN B Thippeswamy
Nov 5, 2016·Toxicon : Official Journal of the International Society on Toxinology·Lourdes DiasStephen Hyslop
Jan 11, 2012·Revista Da Sociedade Brasileira De Medicina Tropical·Ricardo Augusto Monteiro de Barros AlmeidaBenedito Barraviera
Dec 28, 2017·BioMed Research International·Lluvia Arteaga FigueroaVera L Petricevich
Mar 10, 2018·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Wen-Jun LiuYe Xu
Jan 27, 2019·Toxins·Marie-France Martin-EauclairePierre E Bougis
Nov 13, 2015·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Chih-Po HsuChien-Hung Liao
May 16, 2020·Biomedicines·Shirin AhmadiAndreas H Laustsen
Jul 7, 2017·BMC Immunology·Olivier GarraudGamal Badr
Jul 28, 2021·Toxicology Letters·Larissa Magalhães AlvarengaMarcel Ivan Ramírez
Aug 12, 2021·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Varan PerananthanNicholas A Buckley

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