Cytokines and tumors of the central nervous system

Glia
E G Van Meir

Abstract

Cytokines are a group of molecules with an extremely broad range of activities on a variety of target cells. This review summarizes the known cytokine and cytokine receptor expression in primary brain tumors and derived cell lines. These expression patterns are compared with those occurring in other CNS diseases, such as virus or bacterial infections, experimental allergic encephalitis, multiple sclerosis, and trauma. A variety of cytokines are expressed during CNS neoplasia; their potential involvement in tumor growth through a variety of mechanisms, such as autocrine or paracrine growth stimulation, angiogenesis, and immune surveillance evasion, are discussed. Finally, results of preliminary therapeutic approaches with cytokines are critically evaluated.

References

Mar 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·W CammerS Gordon
Dec 1, 1978·Infection and Immunity·I LarssonL Strannegård
Dec 11, 1992·Science·A E KochR M Strieter
Dec 1, 1992·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·T Taga, T Kishimoto
Jan 1, 1992·Neurosurgical Review·T NittaL Steinman
Nov 1, 1992·Human Pathology·H A HorstJ S Kovach
May 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·T AokiT Honjo
Aug 1, 1992·Journal of Neurosurgery·J SchneiderD R Hinton
Sep 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·U SanthanamP B Sehgal
Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·B MotroE Keshet
Mar 1, 1991·The Journal of Clinical Investigation·F BussolinoA Mantovani
Jul 1, 1991·Journal of Neuroimmunology·E P CowanS Dhib-Jalbut
Aug 15, 1991·The New England Journal of Medicine·M K Sharief, R Hentges
Jan 1, 1991·Cancer Immunology, Immunotherapy : CII·B P BarnaM L Estes
Oct 1, 1991·Immunology Today·T RoszmanW Brooks
Jul 1, 1990·Clinical and Experimental Immunology·M C KuppnerN de Tribolet
Feb 1, 1991·Journal of Neuroimmunology·K FreiH Link
Mar 1, 1991·The Journal of Clinical Investigation·K SelmajC F Brosnan
Jan 1, 1990·DNA Sequence : the Journal of DNA Sequencing and Mapping·J Locker, G Buzard
Jun 15, 1990·Biochemical and Biophysical Research Communications·K OhnoT Marunouchi
May 1, 1990·Journal of Neuroscience Research·C ThéryM Mallat
Dec 1, 1990·Journal of Neuroimmunology·B P BarnaR M Ransohoff

❮ Previous
Next ❯

Citations

Oct 31, 1998·International Journal of Cancer. Journal International Du Cancer·T A PatrickE J Roy
Jun 9, 1999·International Journal of Cancer. Journal International Du Cancer·S WagnerJ C Tonn
Apr 30, 2002·International Journal of Cancer. Journal International Du Cancer·Alina V BrennerPeter D Inskip
Jan 7, 2004·Journal of the Neurological Sciences·Shauna KirkStephen Karlik
May 10, 2003·Brain Research. Brain Research Reviews·Paul R WalkerPierre Yves Dietrich
Aug 1, 1997·Trends in Neurosciences·M F Mehler, J A Kessler
Feb 10, 2000·Toxicology·D A Lawrence, D Kim
Aug 1, 1997·Progress in Neurobiology·R A Gadient, U H Otten
Nov 20, 2003·Journal of Autoimmunity·S L Kirk, S J Karlik
Feb 3, 2007·Journal of Proteome Research·Fatima W KhwajaErwin G Van Meir
Jun 13, 2002·Neuropathology and Applied Neurobiology·N J Scolding, F G Joseph
Jan 5, 2002·Advances in Anatomic Pathology·Daniel J BratErwin G Van Meir
Apr 16, 2005·Neuro-oncology·Daniel J BratErwin G Van Meir
Apr 16, 2005·Neuro-oncology·Balveen KaurErwin G Van Meir
Apr 14, 2000·Neurosurgery·I F ParneyK C Petruk
Jun 26, 2003·Neurosurgery·Aaron S DumontKevin S Lee
Mar 21, 1998·Biological Chemistry·A SedoE Krepela
Dec 17, 2010·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Stefan Kaluz, Erwin G Van Meir
Oct 23, 1997·Journal of Neuroimmunology·A KlegerisP L McGeer
Feb 6, 2016·Clinical Neurology and Neurosurgery·C Rory GoodwinGeorge I Jallo
Mar 15, 2016·Frontiers in Surgery·Seyed-Mostafa RazaviGordon Li
Jun 24, 2004·Best Practice & Research. Clinical Anaesthesiology·Leman K MutluIngo Bechmann
Jul 23, 2014·Acta Neuropathologica Communications·Francesco GirolamoMaria Trojano
Mar 10, 2001·The American Journal of Pathology·D J Brat, E G Van Meir
Sep 12, 2016·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Manoj KumarD K Dhawan
May 31, 2001·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·W G Mayhan
Jul 11, 2012·Journal of the Egyptian National Cancer Institute·Eman EldebawyMahmoud Elgantiry
Sep 23, 2011·Veterinary Ophthalmology·Frédéric GoulleThomas Dulaurent
Jul 11, 1998·The Journal of Biological Chemistry·S L KiselevG P Georgiev
May 14, 2020·Expert Opinion on Investigational Drugs·Maria B Garcia-FabianiMaria G Castro
Aug 9, 2020·Frontiers in Immunology·Syreeta DeCordovaUday Kishore
Apr 14, 2018·BioMed Research International·Fabliha Ahmed ChowdhuryMuhammad Shahdaat Bin Sayeed
Jun 26, 2010·Journal of Neuro-oncology·Baisakhi Raychaudhuri, Michael A Vogelbaum
Jan 28, 2005·Journal of Neuro-oncology·Balveen KaurErwin G Van Meir
Aug 2, 2021·Cellular and Molecular Life Sciences : CMLS·Mariana MedeirosMaría Sol Brassesco

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.