PMID: 11923115Mar 30, 2002Paper

Cytokines as a link between innate and adaptive antitumor immunity

Trends in Immunology
Filippo Belardelli, Maria Ferrantini

Abstract

Recent studies indicate that cytokines produced by cells of the innate defense system play an essential role in influencing the immune response towards protective antitumor immunity. These cytokines might act as first 'danger signals' in alerting the immune system. By promoting the differentiation and activation of dendritic cells, antigen presentation and T-cell-mediated immune responses, these cytokines could be powerful natural adjuvants for the development of cancer vaccines. With regard to type I interferons - cytokines with a long history of clinical use - this new knowledge could be translated easily into novel strategies for the prevention and treatment of human malignancies.

References

Mar 1, 1995·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·F Belardelli
Dec 1, 1996·Archives of Dermatological Research·H JonuleitA H Enk
Mar 3, 1997·The Journal of Experimental Medicine·L RoggeF Sinigaglia
Feb 25, 1998·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·A HåkanssonL Håkansson
Oct 1, 1998·Cytokine & Growth Factor Reviews·S Gessani, F Belardelli
Feb 2, 1999·The Journal of Experimental Medicine·P MarrackT Mitchell
Jun 8, 1999·European Journal of Immunology·K KimuraY Yoshikai
Aug 4, 1999·Immunology Today·P L Lollini, G Forni
Dec 10, 1999·The Journal of Experimental Medicine·W B BowneA N Houghton
Mar 11, 2000·Immunology·S M TodrykR G Vile
Apr 29, 2000·Current Opinion in Hematology·T L Warren, G J Weiner
Aug 5, 2000·International Journal of Cancer. Journal International Du Cancer·R MeazzaP Musiani
Jan 3, 2001·Blood·T A Fehniger, M A Caligiuri
Jan 13, 2001·Current Opinion in Immunology·S Gallucci, P Matzinger
Apr 5, 2001·Trends in Immunology·I MeleroJ Prieto
Apr 5, 2001·Trends in Immunology·P K DasI C Le Poole
Apr 24, 2001·Cancer Immunology, Immunotherapy : CII·N RenkvistG Parmiani
Jul 28, 2001·Trends in Immunology·M J Smyth, J A Trapani
Sep 28, 2001·Trends in Immunology·D M FruchtS Koyasu
Oct 3, 2001·The Journal of Experimental Medicine·M MohamadzadehJ Banchereau

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Citations

Mar 11, 2011·Inflammatory Bowel Diseases·Nabeetha A NagalingamVincent B Young
Jul 26, 2005·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Kristian Strømgaard
Dec 1, 2010·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Aqeel JaveedYong Zhao
May 13, 2005·Cancer Immunology, Immunotherapy : CII·K E de Visser, L M Coussens
Nov 19, 2009·Cancer Immunology, Immunotherapy : CII·Mohamed Labib Salem, David J Cole
Mar 17, 2010·Amino Acids·Xin LinXiaoyuan Chen
Aug 25, 2007·Cancer Metastasis Reviews·James E TalmadgeEric Scholar
Jan 22, 2013·Applied Biochemistry and Biotechnology·Nidhi Chaubey, Siddhartha Sankar Ghosh
Jan 30, 2004·Cytokine & Growth Factor Reviews·Simone MocellinMario Lise
Jun 25, 2003·Biochemical and Biophysical Research Communications·Eva GeliusHåkan Steiner
Dec 14, 2002·Human Immunology·Lars Rönnblom, Gunnar V Alm
Sep 18, 2002·Journal of Dermatological Science·Brian J Nickoloff
Dec 24, 2002·Trends in Immunology·Simone MocellinFrancesco M Marincola
Jul 16, 2003·International Immunopharmacology·Françoise Audibert
Jul 7, 2010·Cell Research·Adam C Soloff, Simon M Barratt-Boyes
Jun 24, 2006·Nature Reviews. Cancer·Ana P CastanoMichael R Hamblin
Sep 20, 2007·Leukemia·D RibattiA Vacca
Jul 15, 2003·Mediators of Inflammation·Krzysztof SzylloAnna Kamer-Bartosinska
Jun 6, 2007·The Journal of Experimental Medicine·Martijn A NolteCaetano Reis e Sousa
Jan 7, 2003·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Stefano M SantiniFilippo Belardelli
Feb 3, 2005·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Réda Hadj-SlimanePierre Bobé
Jan 24, 2007·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Jonathan LarkinSeng-Lai Tan
Apr 29, 2008·International Immunology·Béatrice Le Maux ChansacFathia Mami-Chouaib
May 18, 2011·Transplantation·Maria Cecilia S FreitasJerzy W Kupiec-Weglinski
Feb 6, 2008·Molecular and Cellular Biology·Padmaja GadeDhananjaya V Kalvakolanu
Mar 20, 2010·The Journal of Clinical Investigation·Jadwiga JablonskaSiegfried Weiss
Feb 8, 2005·Genome Biology·Dirk NagorsenMonica C Panelli
Jul 11, 2013·Future Oncology·Zhang PengjunTian Yaping
Sep 11, 2013·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Dafne Müller
Dec 7, 2007·Radiation and Environmental Biophysics·Aneta ChedaMarek K Janiak

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