PMID: 3756823Nov 1, 1986Paper

Cytologic detection of condylomas and cervical intraepithelial neoplasia of the uterine cervix with histologic correlation

Cancer
S M Selvaggi

Abstract

Human papillomavirus (HPV) has been implicated as an important etiologic factor in cervical carcinoma. This study evaluates the efficacy of cytology as a screening tool in the detection of cervical lesions with koilocytotic features. Cervical smears and biopsy specimens from 76 women seen between January 1983 and October 1985 were reviewed. The histologic categories consisted of koilocytotic lesions (flat condylomas) with minimal cellular atypia, CIN I, II, III, with surface koilocytes showing cellular atypia (atypical koilocytosis), CIN III with a contiguous lesion as defined in categories 1 and 2, negative biopsies. Histologically, five cases showed flat condylomas with minimal cellular atypia, 65 showed cervical intraepithelial neoplasia (CIN) with atypical koilocytosis and two showed negative biopsies. Cytologically, in all cases of flat condyloma with minimal cellular atypia (5+5), CIN I with atypical koilocytosis (39/39), and CIN III with a contiguous condylomatous lesion (4/4) both koilocytes and, in the latter two categories, dysplastic cells were identified in the cervical smears. In 7/9 cases of CIN II and 9/17 cases of CIN III with atypical koilocytosis, smears showed both atypical koilocytes and dysplastic cells. In...Continue Reading

References

Aug 15, 1981·American Journal of Obstetrics and Gynecology·R J KurmanA B Jenson
Oct 1, 1981·Gynecologic Oncology·A Meisels, C Morin
Jan 1, 1982·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·A MeiselsM Casas-Cordero
Oct 1, 1981·Gynecologic Oncology·Y S FuR M Richart
Mar 30, 1956·Annals of the New York Academy of Sciences·L G KOSS, G R DURFEE

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Citations

Mar 2, 2006·Environmental Health Perspectives·Kathleen M McCartyDavid C Christiani
Jun 5, 1991·European Journal of Obstetrics, Gynecology, and Reproductive Biology·U HørdingB Norrild
Dec 1, 1994·Critical Reviews in Oncology/hematology·E BurghardtH Pfister

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