PMID: 8599913Nov 1, 1995Paper

Cytologic findings of collecting duct carcinoma of the kidney

Diagnostic Cytopathology
N P CarawayN G Ordóñez

Abstract

We report the cytologic features of eight fine-needle aspirations (FNA) and eight exfoliative specimens of collecting duct carcinoma (CDC) obtained from six patients. The four men and two women ranged in age from 27 to 69 years (mean = 45 yr) and all had advanced stage disease at presentation (one stage III, five stage IV). Five of the six patients died of widespread disease, and one is alive and well (mean survival, 28 mo; range, 11-48 mo). The smears of the FNA and exfoliative specimens were scantly to moderately cellular. Tumor cells showed moderate pleomorphism and were arranged primarily in cohesive groups that rarely had a papillary configuration. Nuclei had irregular nuclear contours, coarse chromatin, and one to three nucleoli. In the majority of cases the cytoplasm was finely vacuolated, and occasionally there were large intracytoplasmic vacuoles. Intracytoplasmic mucin was demonstrated in two aspirates. Psammoma bodies were present in four of the seven fluids. In two patients, the cytologic diagnosis was supported by positive immunostaining for high-molecular-weight keratin and Ulex europaeus agglutinin I lectin. Leu M-1 was focally positive in one case and negative in the other. The cytologic features of CDC were rea...Continue Reading

References

Aug 1, 1992·Histopathology·L FüzesiC Mittermayer
Jul 1, 1991·Genes, Chromosomes & Cancer·G KovacsH F Kung
Jan 1, 1991·Diagnostic Cytopathology·R DekmezianN Shabb
Apr 1, 1990·Human Pathology·S M KennedyR D Neumann
Mar 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·G KovacsJ Sümegi
Jan 1, 1985·Scandinavian Journal of Urology and Nephrology·T Nørgaard, P Skaarup
Nov 1, 1986·Histopathology·S Fleming, H J Lewi
Dec 1, 1987·Urology·J H Mydlo, R H Bard
Mar 1, 1969·The Journal of Urology·C J RobsonW Anderson
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Mar 1, 1980·American Journal of Clinical Pathology·P K O'Brien, Y C Bedard
Jan 1, 1994·Diagnostic Cytopathology·L J Layfield
Jan 1, 1993·Histopathology·G Kovacs
Apr 1, 1993·British Journal of Urology·M A DimopoulosJ Ro
Jan 1, 1993·Diagnostic Cytopathology·T L Johnson, S R Kini

❮ Previous
Next ❯

Citations

Apr 25, 1997·Cancer·A A RenshawE S Cibas
Jul 25, 1998·Cancer·A A RenshawS R Granter
Dec 14, 2004·Cancer·Lina AssadNancy P Caraway
Jun 16, 2009·Diagnostic Cytopathology·Carla L EllisQing Kay Li
Sep 25, 2003·Diagnostic Cytopathology·Maria SironiMaurizio Spinelli
Dec 8, 2007·Diagnostic Cytopathology·José García-SolanoFrancisco José Jiménez-Penick
Jun 15, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·M LiL S Minsky

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.