Cytological features of basal cell adenoma of salivary glands: Analysis of 19 cases emphasizing stromal spindle cells

Diagnostic Cytopathology
Mitsuaki IshidaKoji Tsuta

Abstract

Basal cell adenoma (BCA) of the salivary gland is a relatively rare benign tumor. Although the presence of stromal spindle cells is a characteristic histopathological feature, this finding has not been the focus of much attention in the cytodiagnosis of BCA. Thus, we analyzed the cytological features of BCA, especially the presence of stromal spindle cells. Patients who were histopathologically diagnosed with BCA and underwent preoperative fine-needle aspiration cytological examination were enrolled in this study. The cytological characteristics including arrangement and shape of the neoplastic cells, nuclear and cytoplasmic features, and the presence of stromal spindle cells were reviewed. Nineteen patients were enrolled in the study. The cytological specimens were cellular and composed of small or large clusters or both. The neoplastic cells had scant cytoplasm and small round to oval nuclei. Basement membrane-like material was observed in 57.9%, and peripheral palisading was noted in 84.2%. Loose aggregates of stromal spindle cells were present in 63.2%, and the stromal spindle cells shown in the histological examination of 85.7% of cases were expressed in the cytological specimens. This study clearly demonstrated the relati...Continue Reading

References

Oct 4, 2007·Acta Cytologica·Hitoshi HaraTakashi Saku
Mar 8, 2011·Diagnostic Cytopathology·Nalini GuptaArvind Rajwanshi
Aug 16, 2011·Cytopathology : Official Journal of the British Society for Clinical Cytology·B VicandiJ M Viguer
Sep 5, 2015·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Emanuela OrtolaniAntonella Coli
Jun 4, 2016·The American Journal of Surgical Pathology·Vickie Y JoJeffrey F Krane
May 4, 2018·Cytopathology : Official Journal of the British Society for Clinical Cytology·L J LayfieldE D Rossi

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Citations

Sep 12, 2019·Archives of Pathology & Laboratory Medicine·Richard L Cantley
Sep 5, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Mirna Scalon CordeiroSérgio Vitorino Cardoso

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