PMID: 824323Oct 1, 1976Paper

Cytology of myeloma cells

Journal of Clinical Pathology
F G HAYHOE, Z Neuman


A cytological, cytochemical, and cytometric study of plasma cells from 195 cases of multiple myeloma showed that, contrary to earlier reports, flaming cells, thesaurocytes, and intranuclear inclusions are not confined to IgA-secreting cases but are common also in IgG and Bence Jones varieties of myeloma. IgA-secreting cells are not larger, nor do they have a lower nuclear cytoplasmic ratio than other myeloma cells. On average, for a given mass of tumour, Bence-Jones, IgG, and IgA varieties of myeloma produce amounts of paraprotein in the ratio 1 to 1-6 to 2-7.


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Sep 16, 1967·British Medical Journal·J R Hobbs
Jun 1, 1969·British Journal of Haematology·J R Hobbs
Dec 1, 1965·American Journal of Clinical Pathology·J E MaldonadoA L Brown

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