PMID: 11926743Apr 3, 2002Paper

Cytomegalovirus in solid organ transplantation

Transplant Infectious Disease : an Official Journal of the Transplantation Society
R H Rubin

Abstract

Despite substantial advances made in controlling the effects of cytomegalovirus (CMV) infection, it remains the single most important pathogen in solid organ transplantation (SOT). Because CMV shares some characteristics with other human herpesviruses, it is also an important model system for understanding the actions of herpesviruses 6 and 7, Epstein-Barr virus (EBV) and, potentially, hepatitis C and B. As the lessons learned from HIV influenced our thinking about other viral infections (e.g. importance of viral load), so too what is learned about CMV will be applied to other herpesviruses. The pervasive nature of CMV and the common problems posed by this virus prompted the convening of a panel of experts in the field of SOT to discuss issues associated with CMV in transplant recipients. This supplement reflects the presentations and discussions at this symposium, including the clinical implications of CMV drug resistance, economic impact of CMV on transplant programs, the rationale for CMV hyperimmune globulin (CMW-IGIV, CytoGam) in SOT, antibody inhibition of CMV, hypogammaglobulinemia, role of CMV in allograft vasculopathy, and the clinical use of CytoGam therapy in a variety of SOT patients. A number of questions during th...Continue Reading

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Citations

Mar 20, 2003·Transplantation Proceedings·L KrogerusI Lautenschlager
May 11, 2012·Enfermedades infecciosas y microbiología clínica·Carlos CerveraCarlos Lumbreras
Mar 29, 2011·Transplantation Proceedings·H Tayebi-KhosroshahiN Badrogli
Jan 18, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Dimitra MitsaniCornelius J Clancy
Feb 5, 2009·Clinical Transplantation·Lara Danziger-Isakov, G Mark Baillie
Dec 5, 2008·Transplant Infectious Disease : an Official Journal of the Transplantation Society·R L BradyP Maxwell
Jul 16, 2010·Transplant Infectious Disease : an Official Journal of the Transplantation Society·S BatailleH Vacher-Coponat
Mar 20, 2013·Journal of Medical Virology·Heli HarvalaIngolfur Johannessen
Jul 5, 2006·Seminars in Pediatric Surgery·Monica Fonseca-Aten, Marian G Michaels
May 19, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Gerhard OpelzAndrea Ruhenstroth
Jan 31, 2020·Frontiers in Immunology·Jose Luis SantiagoAna Isabel Sánchez-Fructuoso

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