Abstract
Despite substantial advances made in controlling the effects of cytomegalovirus (CMV) infection, it remains the single most important pathogen in solid organ transplantation (SOT). Because CMV shares some characteristics with other human herpesviruses, it is also an important model system for understanding the actions of herpesviruses 6 and 7, Epstein-Barr virus (EBV) and, potentially, hepatitis C and B. As the lessons learned from HIV influenced our thinking about other viral infections (e.g. importance of viral load), so too what is learned about CMV will be applied to other herpesviruses. The pervasive nature of CMV and the common problems posed by this virus prompted the convening of a panel of experts in the field of SOT to discuss issues associated with CMV in transplant recipients. This supplement reflects the presentations and discussions at this symposium, including the clinical implications of CMV drug resistance, economic impact of CMV on transplant programs, the rationale for CMV hyperimmune globulin (CMW-IGIV, CytoGam) in SOT, antibody inhibition of CMV, hypogammaglobulinemia, role of CMV in allograft vasculopathy, and the clinical use of CytoGam therapy in a variety of SOT patients. A number of questions during th...Continue Reading
References
Aug 1, 1992·Transplantation·T H TheW J van Son
Aug 1, 1991·The Journal of Infectious Diseases·A P van den BergT H The
Aug 1, 1991·Transplantation·J TsevatA S Levey
Mar 1, 1991·The Annals of Thoracic Surgery·R T PalacH S Floten
Oct 22, 1987·The New England Journal of Medicine·D R SnydmanA S Levey
Jul 1, 1987·Antimicrobial Agents and Chemotherapy·E J WilsonR H Rubin
Nov 1, 1985·The Journal of Infectious Diseases·M HoR L Hardesty
Apr 1, 1986·Clinical Immunology and Immunopathology·R H RubinD N Medearis
May 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R C WalkerC V Paya
Nov 1, 1993·The Journal of General Virology·J SteinS Prösch
Feb 1, 1993·The Journal of Infectious Diseases·A GrefteT H The
May 27, 1997·Transplantation·D MutimerE Elias
Nov 5, 1997·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·D J MutimerE Elias
May 23, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A S KutzaG Bein
May 23, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M Ho
Jun 12, 1998·The New England Journal of Medicine·J A Fishman, R H Rubin
Mar 9, 1999·Mayo Clinic Proceedings·D H DockrellC V Paya
Apr 30, 1999·Transplantation·D C BrennanG G Singer
May 13, 1999·The New England Journal of Medicine·D LowanceI C Lee
Jul 7, 1999·Circulation·H A ValantineJ S Schroeder
Oct 27, 1999·Journal of Medical Virology·P D GriffithsV C Emery
Jan 11, 2000·Transplantation·A HumarA J Matas
Feb 11, 2000·The Journal of Infectious Diseases·A M Kas-DeelenT H The
Jun 9, 2001·Transplant Infectious Disease : an Official Journal of the Transplantation Society·A Durandy
Jun 29, 2001·Transplant Infectious Disease : an Official Journal of the Transplantation Society·P ReinkeH D Volk
Jun 29, 2001·Transplant Infectious Disease : an Official Journal of the Transplantation Society·R H RubinJ A Fishman
Apr 1, 1995·Virology·S PröschD H Krüger
Apr 3, 2002·Transplant Infectious Disease : an Official Journal of the Transplantation Society·D Weill
Apr 3, 2002·Transplant Infectious Disease : an Official Journal of the Transplantation Society·M R Zamora
Citations
Mar 20, 2003·Transplantation Proceedings·L KrogerusI Lautenschlager
May 11, 2012·Enfermedades infecciosas y microbiología clínica·Carlos CerveraCarlos Lumbreras
Mar 29, 2011·Transplantation Proceedings·H Tayebi-KhosroshahiN Badrogli
Jan 18, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Dimitra MitsaniCornelius J Clancy
Oct 25, 2008·Seminars in Immunology·Michal PyzikSilvia M Vidal
Jul 1, 2008·Transplantation Proceedings·R B LimaY A S Sens
Nov 21, 2007·Transplantation Proceedings·M ZakliczyńskiM Zembala
Feb 5, 2009·Clinical Transplantation·Lara Danziger-Isakov, G Mark Baillie
Dec 5, 2008·Transplant Infectious Disease : an Official Journal of the Transplantation Society·R L BradyP Maxwell
Mar 15, 2008·Clinical Transplantation·Albert J EidRaymund R Razonable
Jul 16, 2010·Transplant Infectious Disease : an Official Journal of the Transplantation Society·S BatailleH Vacher-Coponat
Mar 20, 2013·Journal of Medical Virology·Heli HarvalaIngolfur Johannessen
Oct 19, 2010·Transplant Immunology·Olga TichaJiri Litzman
Jul 5, 2006·Seminars in Pediatric Surgery·Monica Fonseca-Aten, Marian G Michaels
Jan 3, 2006·Transplantation Proceedings·A BordilsJ M Crúz
May 19, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Gerhard OpelzAndrea Ruhenstroth
Dec 1, 2007·Transplant Immunology·Leena KrogerusIrmeli Lautenschlager
Apr 22, 2015·Transplantation Proceedings·B-H ChoiD J Han
Aug 8, 2014·Journal of Virology·Fabiola M BittencourtWilliam E Miller
May 14, 2019·Pediatric Transplantation·Shaun D MendenhallLawrence S Levin
Mar 28, 2003·The Journal of Parasitology·B SkotarczakM Sawczuk
Jan 31, 2020·Frontiers in Immunology·Jose Luis SantiagoAna Isabel Sánchez-Fructuoso
Jun 6, 2018·Frontiers in Immunology·Hana RohnVera Rebmann