PMID: 9181380May 1, 1997Paper

Cytomegalovirus infection in newborns and their family members: polymerase chain reaction analysis of isolates

Infection
I E SouzaJ F Bale

Abstract

Polymerase chain reaction (PCR) analysis with primers for the pp65, a-sequence, glycoprotein B, and major immediate early genes of human cytomegalovirus (CMV) was used to study five congenitally-infected infants and their CMV-infected family members. Family members excreting CMV included three mothers and two siblings. The PCR results indicated that the CMV strain excreted by each infant was indistinguishable from that excreted by the corresponding family member. By contrast, the molecular profiles of the CMV strains were distinct between families, indicating that the PCR algorithm described in this study is a useful method for analyzing CMV strains.

References

Feb 16, 1991·JAMA : the Journal of the American Medical Association·J R MurphJ F Bale
Jul 1, 1991·Journal of Clinical Microbiology·D H Persing
Oct 10, 1986·JAMA : the Journal of the American Medical Association·S StagnoC A Alford
Feb 1, 1987·The Journal of Infectious Diseases·S A PlotkinD R O'Boyle
May 28, 1987·The New England Journal of Medicine·R F PassC A Alford
Sep 1, 1993·Journal of Clinical Microbiology·J F BaleJ R Murph

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Citations

Mar 25, 2004·Nature Reviews. Immunology·Mary M Stevenson, Eleanor M Riley
Mar 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·J LanghorneT von der Weid
Aug 22, 2000·The Journal of Experimental Medicine·V PasquettoF V Chisari
Dec 5, 2002·Shock·Masakatsu GotoMohammed M Sayeed
Sep 10, 2008·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Stephanie A S StarasMichael J Cannon

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