Cytopathological findings of proliferating pilomatricoma misdiagnosed as a malignant parotid gland tumor

Diagnostic Pathology
Nozomu KuroseSohsuke Yamada

Abstract

Pilomatricoma is a relatively common benign cutaneous adnexal neoplasm with differentiation towards the hair matrix, inner sheath of hair follicle and hair cortex. Proliferating pilomatricoma is a rare variant of pilomatricoma that can rapidly increase and may be misidentified as a malignant tumor. We herein report the cytopathological findings of proliferating pilomatricoma misdiagnosed as a malignant parotid tumor. A 64-year-old man noticed an acne-like nodule in the left parotid region. It was painless, but it increased to a maximum diameter of 4.5 cm over 2 years. Clinically, left parotid gland carcinoma was suspected, and fine-needle aspiration cytology was performed. Clusters of epithelial cells were observed in a necrotic background, and malignant epithelial cells derived from salivary glands were suspected. Histologically, the resected tumor was diagnosed as proliferating pilomatricoma composed of basophilic cells and shadow cells apart from the parotid gland. However, on a re-evaluation of the cytological specimens, the irregular-shaped epithelial cells were considered to be from basophilic cells. Shadow cells with nuclear disappearance were also confirmed. Tumor recurrence and metastasis have not been observed in the ...Continue Reading

References

Aug 1, 1996·The American Journal of Dermatopathology·S KadduH Kerl
Apr 1, 1997·Journal of Cutaneous Pathology·S KadduH Kerl
Jun 9, 2004·Annals of Diagnostic Pathology·Luciano B Lemos, Randall W Brauchle
Jul 20, 2007·Cytopathology : Official Journal of the British Society for Clinical Cytology·S SinghA K Mandal
Mar 19, 2016·Diagnostic Cytopathology·Salvatore BellafioreSimonetta Piana

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Citations

Sep 29, 2020·Pediatric Dermatology·Lindsay McCormackKaren Wiss

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