PMID: 39171May 25, 1979

Cytoplasmic gel and water relations of axon

The Journal of Membrane Biology
C S SPYROPOULOS

Abstract

A previous method of measuring the swelling pressure (delta IIg) of the cytoplasmic gel of the giant axon of Loligo vulgaris was refined. The estimates of delta IIg made with the improved method were consistent with those made with the earlier method. In these methods the activity of the solvent in the gel is measured by increasing the activity of the solvent in the internal phase of the gel by application of hydrostatic pressure to the gel directly. Comparable values for the activity of the solvent in the gel were obtained also by an alternate method, in which the deswelling of the gel is measured upon decreasing the activity of the solvent in the external phase by addition of a nonpenetrating high mol wt polymer (i.e., Ficoll). Additional support was obtained for the earlier suggestion that delta IIg contributes to the swelling and shrinkage pattern of the whole axon. In part, the new evidence involved two consecutive direct measurements of intraxonal pressure. The first measurement was that of a mixed pressure composed of delta IIg and delta IIm (delta IIm being the effective osmotic pressure due to the intra-extraxonal gradient in the activity of mobile solutes). The subsequent measurement was that of delta IIg alone. The l...Continue Reading

References

Sep 1, 1991·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M A Linshaw
Jan 1, 1980·Upsala Journal of Medical Sciences·C S SPYROPOULOS
Feb 28, 2006·Journal of Controlled Release : Official Journal of the Controlled Release Society·Abdel Kareem AzabAbraham Rubinstein
Feb 1, 1990·British Journal of Addiction·C SchmidtG Ames
Jan 15, 2019·Molecular Biology of the Cell·T J Mitchison

Citations

Aug 1, 1977·Biophysical Journal·R E Godt, D W Maughan
Apr 7, 1977·The Journal of Membrane Biology·C S SPYROPOULOS
Apr 7, 1977·The Journal of Membrane Biology·C S SPYROPOULOS
Dec 30, 1972·Journal of Molecular Biology·I Matsubara, G F Elliott
Jan 1, 1972·International Review of Cytology·R B Wuerker, J B Kirkpatrick
May 1, 1972·The Journal of Physiology·L E Ford, R J Podolsky
May 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·C S SPYROPOULOS, T Teorell
Nov 1, 1966·The Journal of General Physiology·A R FreemanH Grundfest
Jul 1, 1958·The American Journal of Physiology·R O BRADYI TASAKI
Jun 18, 1958·The Journal of Physiology·P C CALDWELL
Sep 1, 1961·The American Journal of Physiology·I TASAKI, C S SPYROPOULOS
Feb 1, 1960·Journal of Neurochemistry·C S SPYROPOULOS
May 1, 1960·The Journal of General Physiology·R VILLEGAS, G M VILLEGAS
Oct 16, 1950·The Journal of Physiology·D K HILL

Related Concepts

Protoplasm
Hydrostatic Pressure
Axon
Illex
Gel
Hydrogen-Ion Concentration
Metazoa
Osmotic Stress
Seawater

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