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Cytoplasmic nanojunctions between lysosomes and sarcoplasmic reticulum are required for specific calcium signaling

bioRxiv

Jan 28, 2014

Nicola FameliAllan M Evans

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Abstract

We demonstrate how nanojunctions between lysosomes and sarcoplasmic reticulum (L-SR junctions) serve to couple lysosomal activation to regenerative, ryanodine receptor-mediated cellular calcium (Ca2+) waves. In pulmonary artery smooth muscle cells (PASMCs) nicotinic acid adenine dinucle...read more

Mentioned in this Paper

Ryanodine Receptor Calcium Release Channel
Junctional
Cytoplasmic
RYR3 gene
Proximal
Sarcoplasmic Reticulum ATPase
Study
Simulation
Sarcoplasmic Reticulum
Calcium [EPC]
2
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Cytoplasmic nanojunctions between lysosomes and sarcoplasmic reticulum are required for specific calcium signaling

bioRxiv

Jan 28, 2014

Nicola FameliAllan M Evans

DOI: 10.1101/002196

Abstract

We demonstrate how nanojunctions between lysosomes and sarcoplasmic reticulum (L-SR junctions) serve to couple lysosomal activation to regenerative, ryanodine receptor-mediated cellular calcium (Ca2+) waves. In pulmonary artery smooth muscle cells (PASMCs) nicotinic acid adenine dinucle...read more

Mentioned in this Paper

Ryanodine Receptor Calcium Release Channel
Junctional
Cytoplasmic
RYR3 gene
Proximal
2

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