PMID: 9450634Feb 5, 1998Paper

Cytoskeletal characterization of arteriovenous epithelioid cells

Histochemistry and Cell Biology
F GölfertR H Funk

Abstract

Data on the cytoskeleton of epithelioid cells in arteriovenous anastomosis (AVA) are sparse, but there is evidence that the (myo)-epithelioid cells of the AVAs represent a specialized smooth muscle cell type with less contractile properties. We demonstrated the expression of alpha-smooth muscle actin, smooth muscle myosin, calponin, caldesmon, and caveolin in epithelioid cells of rabbit ear and in human toes, finger tips, and glomus tumors by means of indirect immunofluorescence techniques and immunoelectron microscopy. Epithelioid cells in rabbit ear did not express vimentin, but it was present in human toes, finger tips, and glomus tumors. Epithelioid cells in human toes, finger tips, and glomus tumors did not express desmin, but it was present in rabbit ear. Epithelioid cells did not express cytokeratins. The epithelioid cells examined showed only a weak expression of the protein smoothelin, which occurs exclusively in contractile smooth muscle cells. Immunoelectron microscopical demonstration of (alpha-smooth muscle actin revealed a striking difference in the arrangement of actin filaments in the epithelioid cells as compared to that in the smooth muscle cells of blood vessels. The epithelioid cells contained a loose array ...Continue Reading

Citations

Oct 16, 2010·International Journal of Hypertension·Daniel Casellas
Apr 23, 2002·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Nalini M RajamannanStephen W Carmichael
Sep 1, 2007·Journal of Cellular and Molecular Medicine·Vladimír PucovskýThomas B Bolton
Jun 30, 2000·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M MidttunW P Paaske
Nov 28, 2019·Clinical Hemorheology and Microcirculation·H SieversR M Hirschberg

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