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Cytotoxic activity of copper(ii), nickel(ii) and platinum(ii) thiosemicarbazone derivatives: interaction with DNA and the H2A histone peptide

Metallomics : Integrated Biometal Science

Oct 16, 2019

Franco BisceglieGiorgio Pelosi

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Abstract

Metal complexes still represent promising pharmacological tools in the development of new anticancer drugs. Bis(citronellalthiosemicarbazonate)nickel(ii) is a metal compound extremely effective against leukemic and NCS cancer cell lines. Preliminary experiments performed with this compo...read more

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Analogs & derivatives
Antineoplastic Agents
Malignant Neoplasms
Chromatin
Copper
Crohn Disease
DNA
Histones
Laboratory Procedures
Leukemia
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Cytotoxic activity of copper(ii), nickel(ii) and platinum(ii) thiosemicarbazone derivatives: interaction with DNA and the H2A histone peptide

Metallomics : Integrated Biometal Science

Oct 16, 2019

Franco BisceglieGiorgio Pelosi

PMID: 31502621

DOI: 10.1039/c9mt00166b

Abstract

Metal complexes still represent promising pharmacological tools in the development of new anticancer drugs. Bis(citronellalthiosemicarbazonate)nickel(ii) is a metal compound extremely effective against leukemic and NCS cancer cell lines. Preliminary experiments performed with this compo...read more

Mentioned in this Paper

Analogs & derivatives
Antineoplastic Agents
Malignant Neoplasms
Chromatin
Copper

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