PMID: 7546547Sep 1, 1995Paper

Cytotoxic biflavonoids from Selaginella willdenowii

Phytochemistry
G L SilvaA Douglas Kinghorn

Abstract

Bioactivity-guided fractionation of the leaves of Selaginella willdenowii afforded three known biflavones, 4',7"-di-O-methylamentoflavone, isocryptomerin and 7"-O-methylrobustaflavone, that were significantly cytotoxic against a panel of human cancer cell lines. Non-cytotoxic isolates were also obtained, namely, amentoflavone, bilobetin, robustaflavone and 2",3"-dihydroisocryptomerin, a new dihydrobiflavone. The structure for the new biflavonoid was unambiguously assigned by a combination of spectroscopic methods.

References

Jan 1, 1993·Journal of Natural Products·K LikhitwitayawuidN Ruangrungsi

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Citations

Oct 10, 2006·Archives of Pharmacal Research·Hyun Jun JungDong Gun Lee
Oct 15, 2010·Archives of Pharmacal Research·Eun Mi RohEun-Rhan Woo
Dec 29, 2000·Phytochemistry·J B Harborne, C A Williams
Mar 8, 2013·Journal of Asian Natural Products Research·Hui ZouGui-Shan Tan
Mar 21, 2001·Biological & Pharmaceutical Bulletin·S C MaR C Lin
Dec 25, 2002·Chemical & Pharmaceutical Bulletin·Yao-Haur KuoYa-Ching Shen
Jan 7, 2005·Chemical & Pharmaceutical Bulletin·Biswanath DasBharatam Jagadeesh
Jul 2, 2008·Chemical & Pharmaceutical Bulletin·Xian-Long ChengRui-Chao Lin
Dec 23, 2008·Biochemical and Biophysical Research Communications·Juneyoung LeeDong Gun Lee
Oct 12, 2004·Phytotherapy Research : PTR·Sutapa ChakrabortyR K Bhattacharya
Jan 28, 2005·Magnetic Resonance in Chemistry : MRC·Francisco Geraldo BarbosaEdilberto Rocha Silveira
Dec 29, 2006·Chemistry & Biodiversity·Ramalla Chidananda SwamyAchanta Venkata Narasimha Appa Rao
Sep 17, 2011·Chemistry & Biodiversity·Bin Wu, Jia Wang
Jul 14, 2010·Magnetic Resonance in Chemistry : MRC·Yuan CaoQiang Wang
Apr 1, 2006·Bioorganic & Medicinal Chemistry Letters·Mi Kyeong LeeYoung Choong Kim
May 26, 2015·Bioorganic & Medicinal Chemistry Letters·Hiroaki SasakiKaoru Kinoshita
Jul 26, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·N MiceliM F Taviano
Feb 18, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sheng YuSam Fong Yau Li
Feb 24, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hong YaoXinhua Lin
Feb 26, 2016·Memórias do Instituto Oswaldo Cruz·Dayane Priscilla de Souza QueirozCarla Cardozo Pinto de Arruda
Feb 7, 2018·Journal of Zhejiang University. Science. B·Xavier-Ravi BaskaranWen-Bo Liao
Dec 5, 2012·Beilstein Journal of Organic Chemistry·Chao YangWujiong Xia
Apr 25, 2019·Brazilian Journal of Biology = Revista Brasleira De Biologia·L A R Oliveira-MacêdoJ R G S Almeida
Jan 7, 2021·Briefings in Bioinformatics·Shiv BharadwajVivek Dhar Dwivedi
Apr 1, 1997·Journal of Natural Products·C M SunJ C Ou
Jun 8, 2000·Journal of Natural Products·L C LinC J Chou

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