Cytotoxic diterpenoids and sesquiterpenoids from Pteris multifida

Journal of Natural Products
Xin GeWei-Min Zhao

Abstract

Three new ent-kaurane diterpenoids, named pterokaurane M 1-M 3 ( 1- 3) and three new C 14 pterosin-sesquiterpenoids, named multifidoside A-C ( 4- 6), along with 18 known compounds, were isolated from the whole plants of Pteris multifida . The structures of 1- 6 were established using spectroscopic methods, including extensive 2D NMR and CD analyses. Compounds 4 and 5 showed cytotoxicity against the HepG2 tumor cell line with IC 50 values of less than 10 microM.

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Citations

Jun 17, 2008·Journal of Natural Medicines·Liva HarinantenainaHideaki Otsuka
May 26, 2012·Journal of Natural Products·Wei-Guang WangHan-Dong Sun
Apr 7, 2011·Chemical & Pharmaceutical Bulletin·Fei WangJi-Kai Liu
Dec 24, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bi-Ling WuGuang-Xiong Zhou
Aug 23, 2011·Fitoterapia·Jianqun LiuWei Zhang
May 15, 2015·Journal of Asian Natural Products Research·Gang NiDe-Quan Yu
Dec 31, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jung Wha KimSang Hyun Sung
Mar 3, 2017·Journal of Asian Natural Products Research·Yu-Sheng ShiLi-Yan Tan
Dec 3, 2016·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Yoshihiro Ueda
Aug 21, 2009·Natural Product Reports·James R Hanson
Aug 21, 2009·Natural Product Reports·Braulio M Fraga
Jan 1, 2017·Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe·Hui CaoHenrique D M Coutinho
Sep 20, 2015·Angewandte Chemie·Yoshihiro UedaTakeo Kawabata

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