PMID: 6093343Sep 1, 1984

Cytotoxic immune response of puppies to feline sarcoma virus induced tumors

Veterinary Immunology and Immunopathology
M M SuterC A Holmberg

Abstract

The cytotoxic immune response of puppies to feline sarcoma virus induced tumors was studied. Neonatal puppies were compared with adolescent dogs. Three different types of cytotoxicity were investigated: complement dependent cytotoxicity, T-cell-mediated cytotoxicity and antibody dependent cellular cytotoxicity. The relationship between the spontaneous regression of the sarcoma and the development of the immune system of the puppies is discussed.

Related Concepts

Metazoa
Antibody-Dependent Cellular Cytotoxicity
Hemolytic Complement
Immunologic Tumoricidal Activities
Canis familiaris
Sarcoma Virus, Feline, Snyder-Theilen
Sarcoma, Jensen
TC2 Cells
Papilloma, Shope

Related Feeds

Antibody-Dependent Cell Cytotoxicity

Antibody-dependent cellular toxicity refers to the lysis of a target cell by a non-sensitized effector cell of the immune system as a result of antibodies binding to the target cell membrane and engaging the Fc receptors on the immune effector cells. Find the latest research on antibody-dependent cellular toxicity here.