Apr 25, 2019

Cytotoxic impacts of CuO nanoparticles on the marine microalga Nannochloropsis oculata

Environmental Science and Pollution Research International
Nasrin FazelianMahsa Rahimzadeh

Abstract

The toxic impacts of CuO nanoparticles (NPs) on the marine phytoplankton Nannochloropsis oculata were evaluated by measuring a number of biological parameters. Exposure to different concentrations of CuO-NPs (5-200 mg/L) significantly decreased the growth and content of chlorophyll a of N. oculata. The results showed that CuO-NPs were toxic to this microalga with a half maximal effective concentration (EC50) of 116.981 mg/L. Exposure to CuO-NPs increased the hydrogen peroxide (H2O2) content and induced the membrane damages. Moreover, the concentration of phenolic compounds was increased, while the levels of carotenoids were markedly decreased in comparison to the control sample. The activity of catalase (CAT), ascorbate peroxidase (APX), polyphenol oxidase (PPO) and lactate dehydrogenase (LDH) enzymes significantly was increased in response to CuO-NPs treatments. These results indicated that CuO-NPs stimulated the antioxidant defense system in N. oculata to protect the cells against the oxidative damages. The Fourier-transform infrared spectroscopy (FTIR) analyses showed that the main functional groups (C=O and C-O-C) interacted with CuO-NPs. The images of scanning electron microscopy (SEM) and transmission electron microscopy ...Continue Reading

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Citations

Mentioned in this Paper

Copper dioxide (CuO2)
Hydrogen Peroxide
Carotenoids
Membrane
Perhydrol
Tissue Damage
Antioxidant Effect
Oxidative Stress
Spectroscopy, Fourier Transform Infrared
Evaluation

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