PMID: 6980827Jan 1, 1982Paper

Cytotoxic T lymphocyte lines (CTLL) against a human minor alloantigen

Immunogenetics
K S ZierG R Pierson

Abstract

Cytotoxic T-cell lines were generated following in vitro culture of lymphocytes from a patient suffering from aplastic anemia together with those of his HLA-identical brother, a repeated transfusion donor. The segregation pattern within the family of the determinant(s) detected by these cytotoxic cells strongly suggested that a minor alloantigen(s) was being detected. Testing of the effectors on a panel of unrelated individuals indicated that it was best seen in association with HLA-B7, which was common to both the patient and his sibling donor.

References

Aug 1, 1979·European Journal of Immunology·H von BoehmerW Haas
Jul 14, 1977·Nature·S Gillis, K A Smith
Apr 17, 1975·The New England Journal of Medicine·E ThomasC D Buckner
Nov 1, 1975·The Journal of Experimental Medicine·R D GordonL E Samelson
Jul 1, 1981·Human Immunology·D J Schendel, R Wank
Jul 1, 1981·Journal of Clinical Immunology·J B BurnsR P Lisak

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Citations

Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J YamamotoM Takiguchi
Feb 1, 1993·European Journal of Immunology·Y BeckA Kariyone
Jul 1, 1986·Immunology Today·B Loveland, E Simpson

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