Cytotoxicity of abietane diterpenoids from Perovskia abrotanoides and of their semisynthetic analogues

Bioorganic & Medicinal Chemistry
Yutaka AoyagiTeruo Kurihara

Abstract

Seven known abietane diterpenoids and 11-O- and 12-O-acetylcarnosic acids were isolated from a methanol extract of Perovskia abrotanoides (Labiatae). Structure and cytotoxic activity relationships (SAR) of the natural and semisynthetic analogues of the presently isolated abietane diterpenoids were studied by using P388 murine leukemia cells.

Citations

Jul 20, 2013·Journal of Natural Products·Olga BurmistrovaFrancisco Estévez
Nov 23, 2007·Natural Product Reports·James R Hanson
Jul 24, 2014·Biological Research·Sadaf Naz AshrafSezai Ercisli
May 27, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mariano Walter PertinoGuillermo Schmeda-Hirschmann
Feb 3, 2015·Phytochemistry·Simona BirtićMarc Roller
Nov 2, 2006·Chemical & Pharmaceutical Bulletin·Yutaka AoyagiTeruo Kurihara
Apr 5, 2008·Archiv der Pharmazie·Aurora MolinariArturo San Feliciano
Apr 3, 2010·Journal of Natural Products·Mariano Walter PertinoGuillermo Schmeda-Hirschmann
Dec 2, 2017·The Journal of Organic Chemistry·Zhongle LiZhixiang Xie

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